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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Hair patterns in mice are controlled by both a global system dependent on Fz6 and a local self-organizing system.

Three genes in Arabidopsis are important for plant growth and development by affecting sugar attachment to proteins.

Methotrexate is not proven effective for inducing remission in ulcerative colitis.

Methotrexate is not proven to maintain remission in ulcerative colitis.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

New hair growth corticosterone levels are higher in diabetic mice, indicating long-term stress.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.

Certain genetic variations in the FST gene are linked to better wool quality in Chinese Merino sheep.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.

TIP39 and PTH2R help control calcium levels and skin cell development.

AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.

Type 2 immunity helps control mite growth in hair follicles, preventing damage.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

PRX01, PRX44, and PRX73 are essential for root hair growth in Arabidopsis thaliana.

Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

High mTORC1 activity slows hair growth and causes it to lose color.

A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.

The rhg mutation in mice affects the Oat gene, causing hair growth issues and other symptoms.

EDA signaling is linked to skin disorders, various cancers, and liver disease.

Certain immune cells worsen post-surgery gut paralysis by activating a specific immune response.

Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.

Povidone iodine reduced skin bacteria more than chlorhexidine gluconate, but neither met FDA reduction standards.

A 9-year-old girl with a healthy immune system was successfully treated for a severe fungal scalp infection caused by Microsporum audouinii.