January 2020 in “Turk Dermatoloji Dergisi” In this study, androgenetic alopecia, diagonal earlobe crease, and hairy ear were more frequently observed in men with coronary artery disease compared to controls.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that engineered high-affinity soluble CD200R agonists, including ARQ-234, showed superior efficacy in reducing immune responses in various preclinical models of inflammatory conditions, suggesting potential as a therapeutic for atopic dermatitis and other related diseases.
3 citations
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April 2002 in “The American Journal of Medicine” The document concludes that early diagnosis of Balint's syndrome is crucial for effective treatment and that understanding drug interactions, like between ritonavir and statins, is important for patient care.
107 citations
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April 2014 in “The Plant cell” In this study, researchers showed that the CAP1 gene regulates root hair growth in plants by modulating cytoplasmic ammonium levels and maintaining calcium gradients, highlighting its role in ammonium homeostasis.
December 2014 in “CVR Journal of Science & Technology” This study identified various functional groups and chemical constituents in dried leaves of the medicinal plant Bhringaraj, suggesting their potential use in developing wastewater treatment technologies.
1 citations
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November 2024 in “Diabetes Metabolic Syndrome and Obesity” In this study, researchers found that a specific genetic variant in the INSR gene is linked to severe insulin resistance and hyperandrogenemia in type A insulin resistance syndrome, suggesting the benefit of exon sequencing for accurate diagnosis and treatment.
3 citations
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October 2001 in “British Journal of Ophthalmology” In this case, intralesional cidofovir showed a successful outcome for treating SCC without systemic toxicity, suggesting it may be worth considering alongside surgical excision.
September 1973 in “Primates”
14 citations
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June 1952 in “The BMJ” Phenobarbitone can cause severe and sometimes fatal skin reactions.
36 citations
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March 2005 in “Biotechnology and Bioengineering” This study demonstrated that a novel synthetic amyloid template accelerates the deposition of insulin monomers into amyloid fibrils without a lag time, potentially aiding in vitro screening of amyloid deposition inhibitors.
58 citations
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June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that Atlantic croaker nuclear androgen receptors AR1 and AR2 have different binding affinities for androgens, suggesting that they may mediate distinct physiological actions in teleosts.
In this study on mice, a baricitinib-loaded microneedle patch enhanced hair growth in alopecia areata lesions (68% vs control: 33%, p < 0.05), suggesting it may deliver treatment effectively and pain-free, with fewer systemic side effects.
3 citations
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May 2009 in “Journal of Pediatric Gastroenterology and Nutrition” This report highlights the diagnostic challenge of distinguishing autoimmune hepatitis from visceral leishmaniasis in children, revealing the importance of excluding infectious causes closely mimicking autoimmune features before initiating immunosuppressive therapy.
This study found that a positive feedback loop involving RHD2-derived ROS and Ca2+ influx maintains active growth sites in Arabidopsis root hair cells, influencing cell shape.
66 citations
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January 2001 in “Vitamins and hormones” This chapter reviews the role of androgen receptors in mediating the actions of androgens in specific tissues and provides no new experimental findings.
This case study reports that prolonged high-dose vitamin A intake led to multiple adverse health effects in a young man, which mostly resolved after stopping the supplement, although liver changes persisted.
August 2022 in “Journal of Investigative Dermatology” Baricitinib reduces inflammation and mitochondrial damage in skin cells.
October 2023 in “Indian journal of ophthalmology. Case reports” This case report described acute vision loss in a patient after forehead injections of triamcinolone acetonide for alopecia areata, attributing retinal artery occlusion to embolization by steroid particles.
Baricitinib may reactivate trichilemmal cysts in people with a history of these cysts.
June 2020 in “Zenodo (CERN European Organization for Nuclear Research)” This conference abstract summarizes discussions on human genetics and genetic diseases but reports no new research findings.
January 2024 in “Wiadomości Lekarskie” This source outlines the potential benefits and challenges of integrating advanced care at home programs with hospital medicine, highlighting their implications for healthcare systems and the necessary technological support. Results are not detailed in the abstract.
8 citations
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January 2013 in “International journal of trichology” This report details two cases of alopecia areata with unusual annular and circinate patterns, highlighting atypical morphology of the condition.
1 citations
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July 1991 in “PubMed” This case report describes a patient with adrenomyeloneuropathy, highlighting unusual MRI findings of high signal areas in the right striatum.
6 citations
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June 2023 in “Journal of the European Academy of Dermatology and Venereology” This study observed that inflammatory AIGA is associated with sweat duct inflammation and sweat coil atrophy, while non-inflammatory AIGA involves only sweat coil atrophy, suggesting distinct pathological features between the two.
53 citations
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October 2003 in “Genetics” This study identified a mutation hotspot in the caracul (Ca) locus of mice, implicating the mK6irs1/Krt2-6g gene in hair formation and potentially human hair and skin diseases.
3 citations
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April 2024 in “International Journal of Women’s Dermatology” This article discusses barriers to obtaining JAK inhibitor therapy for patients with alopecia areata and highlights that racial inequities may worsen these difficulties; it calls for further advocacy to improve access.
Defective protein folding due to a mutation is key in ANE syndrome.
10 citations
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February 2008 in “Photochemistry and photobiology” This study suggests that the vitamin D receptor and hairless gene may directly regulate each other via a transcriptional mechanism, potentially explaining phenotypic similarities between atrichia and VDRRIIa rickets.
10 citations
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November 2015 in “Experimental Dermatology” The study observed that mRAGE expression is prevalent in keratinocytes of the healthy human epidermis and may regulate inflammation and apoptosis to maintain skin homeostasis rather than responding to aging processes.
November 2008 in “British Journal of Hospital Medicine” This case report describes a patient's psychiatric and medical journey after a cardiac arrest, focusing on managing agitated behavior without medication, leading to significant improvement in cognitive function over a 5-week hospital stay.