research Major Histocompatibility Complex Class I Chain-Related Gene A Polymorphisms and Extended Haplotypes Are Associated with Familial Alopecia Areata
Certain genetic markers, especially the MICA gene, are linked to alopecia areata.
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research PNU 157706, A Novel Dual Type I and II 5α-Reductase Inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
research Nuclear Factor I-C Regulates TGF-β-dependent Hair Follicle Cycling
Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.
research Nuclear Factor I-C Promotes Proliferation and Differentiation of Apical Papilla-Derived Human Stem Cells In Vitro
NFIC helps human dental stem cells grow and become tooth-like cells.
research Inhibitors of 5α-Reductase Type I in LNCaP Cells from the Roots of Angelica Koreana
Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.
research Alopecia Areata Is Associated With Increased Expression of Heart Disease Biomarker Cardiac Troponin I
People with alopecia areata have higher levels of a heart disease marker than those without hair loss.
research MHC Class I-Like MILL Molecules Are β2-Microglobulin-Associated, GPI-Anchored Glycoproteins That Do Not Require TAP for Cell Surface Expression
MILL molecules are unique immune proteins in mice that don't need TAP to appear on cell surfaces.
research Let-7b Promotes Alpaca Hair Growth via Transcriptional Repression of TGFβR I
Let-7b helps alpaca hair grow by reducing TGFβR I protein.
research Generation of Comparative Pharmacophoric Model for Steroidal 5α-Reductase I and II Inhibitors: A 3D-QSAR Study on 6-Azasteroids
The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
research Update on Melasma—Part I: Pathogenesis
Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
research Study of Human Leukocyte Antigen in 13 Cases of Familial Frontal Fibrosing Alopecia: CYP21A2 Gene p.V281L Mutation from Congenital Adrenal Hyperplasia Linked to HLA Class I Haplotype HLA-A*33:01; B*14:02; C*08:02 as a Genetic Marker
A genetic marker linked to a type of hair loss was found in most patients studied.
research Mutation in 5′ Upstream Region of GCHI Gene Causes Familial Dopa-Responsive Dystonia
A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.
research Plasma-Polymerized Antibacterial Coating of Ovine Tendon Collagen Type I Crosslinked with Genipin and Dehydrothermal-Crosslinked as a Cutaneous Substitute for Wound Healing
The GNP crosslinked scaffold with antibacterial coating is effective for rapid wound healing and infection prevention.
research Chronic Myeloid Leukemia: Part I—Real-World Treatment Patterns, Healthcare Resource Utilization, and Associated Costs in Later Lines of Therapy in the United States
Adolescents with severe alopecia incur significantly higher healthcare costs.
research Autologous Cell Therapy for Aged Human Skin: A Randomized, Placebo-Controlled, Phase I Study
RCS-01 therapy is safe and may improve skin structure by affecting gene expression.
research A Randomized Pilot Study to Compare Hair Follicle Cell Suspensions Prepared Using Trypsin Alone Versus Trypsin in Combination with Collagenase Type I for Transplantation in Vitiligo
Adding collagenase to trypsin improves cell yield and repigmentation in vitiligo treatment.
research Comparison of Postoperative Mid-Term and Long-Term Quality of Life Between Billroth-I Gastroduodenostomy and Billroth-II Gastrojejunostomy After Radical Distal Gastrectomy in Patients With Gastric Cancer: A Cohort Study Based on a Case Registry Database
Both Billroth-I and Billroth-II methods have similar impacts on quality of life after gastric cancer surgery.
research A Phase I, Open-Label, Sequential, Single-Dose Clinical Trial to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of IVL3001, a Finasteride-Based Novel Long-Acting Injection for Androgenetic Alopecia
IVL3001 is safe, effective, and better than oral finasteride for treating hair loss.
research Developing Patient-Reported Outcome Measure for Hair and Skin Disorders
The goal is to create a tool for patients to report their experiences with various hair and scalp disorders.
research Minoxidil and Eye Issues: Coincidence or Fate?
Using Minoxidil for hair loss might cause eye problems, but it's not certain.
research When Can I Stop My Steroids? The Patient Perspective on Glucocorticoid Usage in Adult Inflammatory Myopathy
Patients need better information about the risks of long-term steroid use.
research Expression of Collagen Type I, Skin Fibroblasts, and Macrophages After 1550 nm Erbium Glass Fractional Laser in Androgenic Alopecia
The 1550 nm fractional Er:Glass laser improved hair regrowth in patients with androgenic alopecia, but didn't significantly change collagen type I, skin fibroblasts, or macrophages. More research is needed for optimal results.
research Impact of Diet and Dietary Supplements on Acne Vulgaris
Diet and supplements can significantly affect acne, with some foods and nutrients reducing and others worsening it.
research A Phase I Safety Study of Topical Calcitriol (BPM31543) for the Prevention of Chemotherapy-Induced Alopecia: Final Study Results
Topical calcitriol (BPM31543) is safe for preventing hair loss from chemotherapy and shows some effectiveness.
research Blood Plasma Levels of Heart Disease Biomarker Cardiac Troponin I Are Significantly Increased in Alopecia Areata Affected Individuals
People with alopecia areata have higher levels of a heart disease marker in their blood.
research Finding Evidence of the Efficacy and Safety of Selenium in Treating Hashimoto's Thyroiditis: A Systematic Literature Review
Selenium's effectiveness in treating Hashimoto's thyroiditis is inconclusive.
research Non-Invasive Quick Diagnosis of Cardiovascular Problems from Visible and Invisible Abnormal Changes with Increased Cardiac Troponin I Appearing on Cardiovascular Representation Areas of the Eyebrows, Left Upper Lip, etc. of the Face and Hands: Beneficial Manual Stimulation of Hands for Acute Anginal Chest Pain, and Important Factors in Safe, Effective Treatment
Visible and invisible changes on the face and hands can indicate heart problems, and manual hand stimulation can relieve chest pain.
research Regenerative Medicine Part I: Usage of Porcine Extracellular Matrix in Hair-Loss Prevention, Hair-Restoration Surgery, and Donor-Scar Revision
Pig tissue can be used to prevent hair loss, aid in hair restoration surgery, and improve healing of donor scars.
research Novel Frameshift Mutation in TRPS1 in a Ukrainian Patient with Trichorhinophalangeal Syndrome Type I
A new mutation in the TRPS1 gene was found in a Ukrainian girl with Trichorhinophalangeal syndrome type I.
research Mario Lacouture: How Do I Treat a Patient with Dermatologic Toxicities to EGFR Inhibitors?
Dr. Mario Lacouture recommends preventive and specific treatments for skin side effects caused by EGFR inhibitors to improve patients' quality of life.