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Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Plant adaptogens may help treat skin diseases and improve skin health, but more research is needed to fully understand how they work.

A new gene variant causes glucocorticoid resistance in a mother and son.

Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.

PCOS may increase the risk of mental health issues like depression and anxiety.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

High levels of cortisol in hair show long-term stress which can lower fertility in animals.

Women with irregular periods should be checked for PCOS and treated early to prevent complications, with birth control pills helping to manage symptoms.

First-time mothers had higher stress hormone levels in late pregnancy than mothers who had given birth before.

A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

Secondary amenorrhea has many causes and requires thorough evaluation to treat and restore menstrual cycles.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The document explains how male reproductive hormones work and affect the body.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Thyroid function affects skin health, with a complex interaction between the two.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.

Stress can trigger or worsen alopecia areata.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

Objective assessment is needed to accurately determine medication use and adherence.

Finasteride affects prostate weights and pituitary activity differently with age.

Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.

Hormones control reproduction and are crucial for body balance.

A Shi Tzu dog with high cortisol levels improved after increasing the dose of trilostane.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.