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    Did you mean Hypothalamic-Pituitary-Adrenal Axis?
    Glossary Hypothalamic-Pituitary-Adrenal Axis

    regulates stress response through hormone release from brain and adrenal glands

    The Hypothalamic-Pituitary-Adrenal (HPA) Axis is a complex network involving the hypothalamus, pituitary gland, and adrenal glands, which work together to regulate the body's response to stress. When you encounter stress, the hypothalamus releases corticotropin-releasing hormone (CRH), prompting the pituitary gland to secrete adrenocorticotropic hormone (ACTH), which in turn stimulates the adrenal glands to produce cortisol, a key stress hormone. This system plays a crucial role in maintaining homeostasis and can impact various bodily functions, including immune response and metabolism.

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    1. Targets to treat androgen excess in polycystic ovary syndrome Expert Opinion on Therapeutic Targets · 2015 · 14 citations
    2. Neuroendocrine Determinants of Polycystic Ovary Syndrome International Journal of Environmental Research and Public Health · 2022 · 19 citations
    3. Are Women with Polycystic Ovary Syndrome at Increased Risk of Alzheimer Disease? Lessons from Insulin Resistance, Tryptophan and Gonadotropin Disturbances and Their Link with Amyloid-Beta Aggregation Biomolecules · 2024 · 4 citations
    4. Diagnosis, Pathogenesis and Management of Polycystic Ovary Syndrome InTech eBooks · 2017 · 4 citations
    5. Hair cortisol in polycystic ovary syndrome Scientific reports · 2022 · 2 citations
    6. Microglia: sculptors of the polycystic ovary syndrome (PCOS)-like brain? Reproduction · 2023 · 1 citations
    7. Endocrinopathies and Other Disorders Inducing a Polycystic Ovary Syndrome Phenotype S. Karger AG eBooks · 2012 · 7 citations
    8. Polycystic Ovary Syndrome: Early Detection in the Adolescent Clinical obstetrics and gynecology · 2007 · 50 citations
    9. THE GENETICS OF CYP GENE VARIANTS IN ASSOCIATION WITH POLYCYSTIC OVARY SYNDROME: A NARRATIVE REVIEW Era s journal of medical research · 2024
    10. Androgen Profiling by Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS) in Healthy Normal-Weight Ovulatory and Anovulatory Late Adolescent and Young Women The Journal of Clinical Endocrinology and Metabolism · 2013 · 52 citations
    11. Sindrom policističnih jajnika - izazovi i mogućnosti liječenja Repozitorij Farmaceutsko-biokemijskog fakulteta (Sveučilišta u Zagrebu) · 2019
    12. PCOS: Perspectives from a Pediatric Endocrinologist and a Pediatric Gynecologist Current Problems in Pediatric and Adolescent Health Care · 2013 · 5 citations
    13. Sex Steroid Hormones - Impact on Reproductive Physiology IntechOpen eBooks · 2024 · 1 citations
    14. Health-related quality of life in women with normogonadotropic ovulatory dysfunction: a prospective cohort study Frontiers in Global Women s Health · 2026
    15. Sex Steroid Hormones Directory of Open access Books (OAPEN Foundation) · 2025
    16. A review of hyperandrogenism state in polycystic ovarian syndrome International journal of reproduction, contraception, obstetrics and gynecology · 2023
    17. Neuroendocrine, Neurotransmitter, and Gut Microbiota Imbalance Contributing to Potential Psychiatric Disorder Prevalence in PCOS F&S reports · 2023
    18. Chapter 7 Reproductive Dysfunction in Women with Epilepsy International Review of Neurobiology · 2008 · 34 citations
    19. Irregular Menstruation, Acne, Hirsutism, and the Possibility with PCOS International journal of medical science and clinical invention · 2022
    20. Ovarian hormones and adrenal androgens during a woman's life span Journal of The American Academy of Dermatology · 2001 · 24 citations
    21. Functional Ingredient Mapping in PCOS Formulations: Hormonal Excess International Journal of Innovative Research in Technology · 2025
    22. Polycystic Ovary Syndrome in Adolescents Endocrinology and Metabolism Clinics of North America · 2016 · 18 citations
    23. Physiopathology of polycystic ovary syndrome in endocrinology, metabolism and inflammation Journal of Ovarian Research · 2025 · 70 citations
    24. Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones Neuropsychopharmacology · 2019 · 197 citations
    25. Physiology of the Hypothalamic Pituitary Gonadal Axis in the Male Urologic Clinics of North America · 2016 · 70 citations
    26. Alopecia areata – hyperactivity of the hypothalamic–pituitary–adrenal axis is a myth? Journal of the European Academy of Dermatology and Venereology · 2017 · 5 citations
    27. The impact of levothyroxine on thyroid autoimmunity and hypothalamic–pituitary–thyroid axis activity in men with autoimmune hypothyroidism and early-onset androgenetic alopecia Endokrynologia Polska · 2021 · 1 citations
    28. Gonadal Sex Steroids: Production, Action and Interactions in Mammals InTech eBooks · 2012 · 2 citations
    29. IMPACT OF MERCURY ON SEX HORMONES (LITERATURE REVIEW) Bulletin of Osh State University · 2024 · 1 citations
    30. Hair Cortisol: A Biomarker of Chronic Stress in Animals and its Association with Reproduction Animal Reproduction Update · 2023