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960-990 / 1000+ resultsresearch New developments in our understanding of acne pathogenesis and treatment
We now understand more about what causes acne and this could lead to better, more personalized treatments.
research Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy
PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
![Neuroimmunoendocrine circuitry of the ‘brain-skin connection’](/images/research/ec1f450d-f446-45a3-bd8d-1642dbf27356/small/24955.jpg)
research Neuroimmunoendocrine circuitry of the ‘brain-skin connection’
Stress can worsen skin conditions and stop hair growth by affecting the body's stress response system.
research Impact of estrogens in males and androgens in females
Both estrogens and androgens are important for health in both males and females.
research Hormonal Organization of Sex Differences in Play Fighting and Spatial Behavior
Gonadal hormones may influence sex differences in play fighting in animals, but their effect on human spatial behavior is unclear and needs more research.
![Diagnostic criteria for PCOS: Is there a need for a rethink?](/images/research/252a3be9-1e73-44b2-b687-0481ecd3234f/small/14068.jpg)
research Diagnostic criteria for PCOS: Is there a need for a rethink?
The conclusion is that there's a need for a new conference to establish stricter guidelines for diagnosing Polycystic Ovary Syndrome (PCOS).
![Androgens and ovarian function: translation from basic discovery research to clinical impact](/images/research/58ba045c-e1a3-4169-8b75-9748beb8a43d/small/13353.jpg)
research Androgens and ovarian function: translation from basic discovery research to clinical impact
Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
research Towards the validation of endogenous steroid testing in wildlife hair
Hair analysis for stress and reproductive hormones in wildlife needs more research for accuracy across species.
![Society for Endocrinology guidelines for testosterone replacement therapy in male hypogonadism](/images/research/55aaece1-55fc-4a04-8600-6a44435a87ab/small/17072.jpg)
research Society for Endocrinology guidelines for testosterone replacement therapy in male hypogonadism
Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.
research A systematic review of antiandrogens and feminization in transgender women
Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
research A randomized placebo-controlled study on the effects of pioglitazone on cortisol metabolism in polycystic ovary syndrome
Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
![Nesfatin-1 and Vitamin D levels may be associated with systolic and diastolic blood pressure values and hearth rate in polycystic ovary syndrome](/images/research/79f19c62-a2db-4f5b-85de-df304b239019/small/20981.jpg)
research Nesfatin-1 and Vitamin D levels may be associated with systolic and diastolic blood pressure values and hearth rate in polycystic ovary syndrome
High Nesfatin-1 and low Vitamin D may increase blood pressure and heart rate in women with PCOS.
research Analysis of Hair Cortisol as an Indicator of Chronic Stress in Pigs in Two Different Farrowing Systems
Pigs in farrowing crates and loose-housing systems showed no difference in chronic stress levels as measured by hair cortisol.
![Novel insights into the molecular mechanisms underlying generalized glucocorticoid resistance and hypersensitivity syndromes](/images/research/fb2f7ec3-ef85-48bb-bc2b-e933c3b33e4f/small/20230.jpg)
research Novel insights into the molecular mechanisms underlying generalized glucocorticoid resistance and hypersensitivity syndromes
Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
![Recent advances in the molecular mechanisms causing primary generalized glucocorticoid resistance](/images/research/80c8b0bf-6e83-4859-b17b-7e906e7228a0/small/20244.jpg)
research Recent advances in the molecular mechanisms causing primary generalized glucocorticoid resistance
Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.
![Role of Oxidative Stress in Obese and Nonobese PCOS Patients](/images/research/faf9b129-42ef-428e-ba53-55bbcc8f3e46/small/13090.jpg)
research Role of Oxidative Stress in Obese and Nonobese PCOS Patients
Oxidative stress is higher in women with PCOS, especially if they're obese, and it may increase their risk of heart disease.
research Not the Root of the Problem—Hair Cortisol and Cortisone Do Not Mediate the Effect of Child Maltreatment on Body Mass Index
Child abuse is linked to higher BMI, but not because of hair cortisol or cortisone levels.
research Is increased constitutive skin and hair pigmentation an early sign of puberty?
Darker skin in 10-year-old girls may be an early sign of puberty.
research Age‐dependent regulation by androgens of gene expression in the anterior hypothalamus and stress‐induced release of adrenal hormones in adolescent and adult male rats
Testosterone affects stress hormone levels differently in adolescent and adult male rats.
![Polycystic Ovarian Syndrome: Is It Time to Rename PCOS to HA-PODS?](/images/research/6a7caae1-5794-4c63-8cea-3b1454a92a56/small/13998.jpg)
research Polycystic Ovarian Syndrome: Is It Time to Rename PCOS to HA-PODS?
The article suggests renaming Polycystic Ovarian Syndrome (PCOS) to "Hyperandrogenic Persistent Ovulatory Dysfunction Syndrome" (HA-PODS) for accuracy and consistency, but no final decision was made.
research Evaluation of utility of phenol in alopecia areata
88% phenol is effective for treating alopecia areata.
research Ischemic modified albumin as a new biomarker in predicting of oxidative stress in alopecia areata
Ischemic modified albumin could be a new indicator of oxidative stress in people with alopecia areata.
![Psychological Aspects of Hair Disorders: Consideration for Dermatologists, Cosmetologists, Aesthetic, and Plastic Surgeons](/images/research/22e5dd0e-fe0b-4dde-bc56-da03194a4706/small/13157.jpg)
research Psychological Aspects of Hair Disorders: Consideration for Dermatologists, Cosmetologists, Aesthetic, and Plastic Surgeons
Hair loss can cause stress and mental health issues, so treatments should address both the physical and psychological aspects, involving a team of dermatologists, psychologists, and hair specialists.
research The tail-tale of stress: an exploratory analysis of cortisol levels in the tail-hair of captive Asian elephants
Elephant tail-hair can show past stress levels, matching times when stressful events happened.
![POLYCYSTIC OVARY SYNDROME: PATHOGENESIS, TREATMENT AND SECONDARY ASSOCIATED DISEASES](/images/research/4e341d8a-57d1-4dcf-8836-c429cb22d448/small/15979.jpg)
research POLYCYSTIC OVARY SYNDROME: PATHOGENESIS, TREATMENT AND SECONDARY ASSOCIATED DISEASES
PCOS is a common hormonal disorder in women linked to several health risks and can be managed through various treatments.
research Children’s hair cortisol and hair testosterone concentrations in response to environmental changes: from summer holidays to school
Girls had higher stress hormone levels during school due to social and emotional issues, while boys had higher overall hormone levels with slight changes when school started.
![Stem cell secretome as a mechanism for restoring hair loss due to stress, particularly alopecia areata: narrative review](/images/research/d8afe2c4-ecf2-4742-9a35-ad04b0f46a57/small/13056.jpg)
research Stem cell secretome as a mechanism for restoring hair loss due to stress, particularly alopecia areata: narrative review
Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.
![Dexamethasone, a Synthetic Glucocorticoid, Induces the Activity of Androgen Receptor in Human Dermal Papilla Cells](/images/research/aa76da75-7a26-4b59-8f86-d62710ba4b8c/small/17041.jpg)
research Dexamethasone, a Synthetic Glucocorticoid, Induces the Activity of Androgen Receptor in Human Dermal Papilla Cells
Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.
![Cutaneous Manifestations and Hormonal Changes Among Polycystic Ovary Syndrome Patients at a Tertiary Care Center](/images/research/2fdb78cf-52a3-4cae-a052-55b3e9ed0bed/small/13161.jpg)
research Cutaneous Manifestations and Hormonal Changes Among Polycystic Ovary Syndrome Patients at a Tertiary Care Center
Most women with Polycystic Ovary Syndrome (PCOS) have skin issues like excessive hair, acne, or hair loss. Hormone imbalances are common, and age, certain hormones, and hormone ratios can predict acne. Obesity, infertility, and high cholesterol are also common in these women.