research Role of 5 Alpha-Reductase Inhibitors in the Management of Prostate Cancer
5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.
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180-210 / 213 resultsresearch New Insights Into Testosterone Biosynthesis: Novel Observations From HSD17B3 Deficient Mice
Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
research Biallelic Variants in Lanosterol Synthase (LSS) Cause Palmoplantar Keratoderma-Congenital Alopecia Syndrome Type 2
Certain genetic changes in the LSS gene cause a rare skin and hair condition.
research A Long-Term Follow-Up Study of Men Born with Very Low Birth Weight and Their Reproductive Hormone Profile
Men born very underweight had higher estrogen levels but normal reproduction compared to normal birth weight men.
research The Post-Finasteride Syndrome: Possible Etiological Mechanisms and Symptoms
Post-finasteride syndrome causes lasting sexual, mental, and physical issues, needing more research for solutions.
research Endocrine Functions of the Testes
The testes produce important hormones like testosterone and others that play key roles in male body functions.
research Pharmacology of Anti-Androgens in the Skin
Anti-androgens can help reduce the effects of male hormones on the skin.
research Persistent Gynecomastia Due to Short-Term Low-Dose Finasteride for Androgenetic Alopecia
A man's breast enlargement from low-dose finasteride for hair loss didn't go away, even with treatment, and might be more common than reported.
research Genetics and Epigenetics of Polycystic Ovary Syndrome
Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.
research Effects of Androgen Treatment on Growth in Patients with 5-Alpha-Reductase Type 2 Deficiency
Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.
research Testosterone: The Male Sex Hormone
More research is needed to understand how testosterone is maintained in adult males.
research 46,XY Disorders of Sex Development Due to Type 2 5-Alpha Reductase Deficiency in Three Siblings: A Case Report from a Low-Resource Setting
Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.
research The Diversity of Sex Development: What Conditions Affecting Sex Development Teach Us About Sexual Diversity
Conditions affecting sex development show that sexual diversity is a natural part of human variation.
research Environmental Endocrine Disrupting Chemicals and Their Epigenetic Influence on Androgenetic Alopecia
Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.
research Dihydrotestosterone and 5α-Reductase: Role in Hair Loss and Prostate Health
Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.
research Evaluating the Role of lncRNAs in the Incidence of Cardiovascular Diseases in Androgenetic Alopecia Patients
research 5-Alpha-Reductase Deficiency in a Saudi Girl
A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.
research Dermatoscopy of Hair Shaft Disorders
Dermatoscopy is a useful tool for diagnosing hair disorders and can help choose samples for more detailed analysis.
research The Molecular Basis of Androgen Insensitivity
Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
research Considerations in Genetic Counseling of Transgender Patients: Cultural Competencies and Altered Disease Risk Profiles
Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.
research Pediatric Lichen Planopilaris: Clinicopathologic Study of Four New Cases and a Review of the Literature
Lichen Planopilaris in teens is rare, often misdiagnosed, and responds well to steroids.
research Pharmacologic Management of Pattern Hair Loss
Treat pattern hair loss with finasteride and topical minoxidil.
research The Long-Term Effect of Specific Type II 5α-Reductase Inhibition With Finasteride on Bone Mineral Density in Men: Results of a 4-Year Placebo-Controlled Trial
Finasteride doesn't harm bone density in older men with BPH.
research Male Androgenetic Alopecia: Medical and Surgical Treatments
Finasteride effectively treats male hair loss, increasing length and thickness.
research Dermatological Medications and Local Therapeutics During Pregnancy
Use some skin medications with caution during pregnancy; avoid strong steroids, certain eczema treatments, and systemic retinoids, but many topical treatments and nasal sprays are safe.
research Selections from Current Literature: Androgenetic Alopecia - The Science Behind a New Oral Treatment
New oral treatment, finasteride, effectively and safely treats common hair loss.
research Clinical Evaluation of Superficial Fungal Infections in Children
The study found that scalp ringworm is the most common fungal infection in children and topical treatments work well.
research 5-Alpha-Reductase Inhibitor Treatment for Frontal Fibrosing Alopecia: An Evidence-Based Treatment Update
5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.
research Androgen Antagonists in Androgen Target Tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Safety of Common Medications for Treating Dermatology Disorders in Pregnant Women
Some skin medications are safe for pregnant women, but others pose risks or should not be used.