216 citations
,
October 1997 in “American Journal of Ophthalmology” This study found that unilateral topical latanoprost use for glaucoma was associated with hypertrichosis and increased pigmentation of eyelashes in the treated eye compared to the untreated eye.
125 citations
,
February 2003 in “Journal of the American Academy of Dermatology” This review discusses various forms and categories of hypertrichosis, as well as methods for managing the condition, but does not report new clinical results.
101 citations
,
June 2005 in “Journal of The American Academy of Dermatology” This study observed that postlaser hair removal hypertrichosis occurred in 0.6% of patients and appeared more common in darker skin types, but was a rare phenomenon overall.
73 citations
,
November 1979 in “British Journal of Dermatology” Minoxidil can cause excessive hair growth.
65 citations
,
November 2004 in “Journal of the American Academy of Dermatology” This article reports a case where the IOP-lowering drug bimatoprost was associated with eyelash hypertrichosis.
63 citations
,
April 2003 in “Journal of The European Academy of Dermatology and Venereology” This study found that minoxidil topical solution was associated with a dose-related occurrence of hypertrichosis, especially facial hair, in women treated for androgenetic alopecia.
53 citations
,
August 2015 in “The Italian Journal of Pediatrics/Italian journal of pediatrics” This review discusses congenital generalized hypertrichosis, focusing on its association with complex malformation syndromes, but it presents no new research findings.
46 citations
,
April 1977 in “Southern Medical Journal” In this study, five women with minoxidil-induced hypertrichosis achieved complete hair removal using a calcium thioglycolate depilatory agent, with minimal or no skin irritation.
45 citations
,
November 1979 in “British Journal of Dermatology” This report describes a case of hypertrichosis associated with minoxidil use and suggests that nearly all patients on this drug may experience this side effect.
44 citations
,
April 2013 in “Proceedings of the National Academy of Sciences of the United States of America” This study found a significant association between reduced FGF13 levels and X-linked congenital generalized hypertrichosis, suggesting FGF13's potential role in hair follicle growth and the hair cycle.
44 citations
,
January 1997 in “British Journal of Dermatology” In this study, five women with androgenetic alopecia experienced severe facial and limb hypertrichosis after using 5% topical minoxidil, which resolved after discontinuing the treatment.
39 citations
,
April 2001 in “Journal of The American Academy of Dermatology” This article reviews the side effects of topical latanoprost therapy, particularly the hypertrichosis and pigmentation changes of eyelashes and nearby skin, and reports no new clinical results.
27 citations
,
June 1989 in “Journal of Medical Genetics” This case report describes four patients with hypertrichosis cubiti and short stature, but could not determine a genetic link between hypertrichosis cubiti and skeletal dysplasia.
26 citations
,
April 1977 in “PubMed” This report notes that five women experiencing hypertrichosis as a side effect of minoxidil had successful hair removal using a calcium thioglycolate depilatory agent.
24 citations
,
May 1982 in “Biochemical Pharmacology” These drugs cause hair growth without affecting testosterone or adrenal hormones.
23 citations
,
April 2010 in “Clinical, cosmetic and investigational dermatology” This review discusses the cutaneous application of bimatoprost ophthalmic solution 0.03% for enhancing upper eyelash growth and suggests it is both safe and effective; no new clinical results are reported.
23 citations
,
April 2004 in “American Journal of Ophthalmology” This case report found that topical bimatoprost usage in a female Hispanic patient with open-angle glaucoma was associated with hypertrichosis and increased pigmentation of vellus hairs on the malar region.
22 citations
,
September 2004 in “Journal of The European Academy of Dermatology and Venereology” Bimatoprost can cause longer, thicker, darker eyelashes and eyebrows.
21 citations
,
January 2005 in “Pediatric Dermatology” An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
18 citations
,
January 1997 in “British Journal of Dermatology” In this study, five women with androgenetic alopecia developed severe hypertrichosis on the face and limbs after using 5% topical minoxidil, which resolved after discontinuing the treatment.
17 citations
,
October 2013 in “F1000Research” This case report details a 2-year-old boy who developed generalized hypertrichosis after using 5% minoxidil foam for alopecia areata, highlighting the importance of caution and proper administration instructions for young children.
16 citations
,
August 2002 in “Journal of Interferon and Cytokine Research” In this case study, hypertrichosis in a patient with hemophilia and hepatitis C may have been induced by IFN-alpha treatment, despite the drug usually causing hair loss.
15 citations
,
March 2004 in “American Journal of Ophthalmology” This case report found that topical bimatoprost in a female Hispanic patient with glaucoma led to increased hair growth and pigmentation in the malar region, which resolved after discontinuing use and epilation.
15 citations
,
August 1988 in “Archives of Otolaryngology - Head and Neck Surgery” This paper reports a case of severe hypertrichosis in the external ear canal due to minoxidil use, leading to chronic otitis externa and hearing loss.
14 citations
,
March 2007 in “Pediatric pulmonology” This study found evidence suggesting that hypertrichosis may be an adverse effect of inhaled corticosteroids in children, although it does not always resolve after stopping treatment.
14 citations
,
January 1995 in “Archives of Physical Medicine and Rehabilitation” This case report describes an individual who developed both localized hypertrichosis and ipsilateral dyshidrotic dermatitis following multiple fractures and cast application, with symptom resolution similar to when these conditions occur independently.
12 citations
,
January 2014 in “The Pan African medical journal” In this case report, a 5-year-old girl experienced extensive hypertrichosis after using topical minoxidil lotion unsupervised, which regressed after discontinuation, highlighting the need for medical oversight.
12 citations
,
February 2010 in “Journal of The American Academy of Dermatology” This article discusses the use of cetuximab for recurrent squamous cell skin cancer in palliative care, noting good responses but frequent cutaneous side effects; it presents no new findings.
10 citations
,
February 2016 in “Anais Brasileiros de Dermatologia” This case report describes a 5-year-old child in Brazil who developed generalized hypertrichosis after using topical minoxidil, suggesting caution when using it in children.
10 citations
,
August 2007 in “Journal der Deutschen Dermatologischen Gesellschaft” Individualized treatment plans are crucial for managing excessive hair growth.