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Side effects of drugs can lead to the discovery of new treatments.

This case study highlights the complexity of managing PCOS and its symptoms in transmen, suggesting hormonal fluctuations may lead to symptomatic relief with low dose estradiol.

This case report details a postmenopausal woman with increased libido, hirsutism, and spontaneous orgasms, noting elevated testosterone levels and enlarged ovaries.

This study found a high concordance between subject-reported and clinician-reported Fitzpatrick Skin Phototypes, but 14% of subjects misjudged their skin type, often overestimating it.

This study found that integrating the Theory of Planned Behaviour with the Stimulus-Organism-Response framework improved the prediction of intentions to buy embarrassing products, with subjective norms being significant across drugstore, internet, and multi-channel environments.

This article discusses common dermatologic side effects of psychopharmacologic agents such as eruptions, urticaria, and photosensitivity, but it reports no new research findings.

This study concluded that a 26-year-old woman had autosomal dominantly inherited hereditary cortisol insensitivity, leading to increased adrenocortical cortisol and androgen secretion, which caused clinical symptoms unlike in her male relatives.

This paper reports insights from an Expert Panel convened by the Society for Immunotherapy of Cancer on managing immune-related adverse events (irAEs) following immune checkpoint inhibitor therapy, highlighting surveillance gaps and the need for a comprehensive irAE registry to improve post-treatment care for cancer survivors.

This study examined immune responses to Diphencyprone and found that its induced skin reactions have higher levels of negative immune regulators compared to psoriasis, suggesting differences in immune regulation may contribute to psoriasis chronicity.

This review discusses hypersensitivity reactions to anticoagulants, highlighting the importance of early diagnosis and exploring various diagnostic and management options, but it presents no new clinical findings.

This article reviews 12 newly approved drugs with pediatric indications from 2001, discussing their clinical importance for general pediatricians, but reports no new clinical results.

In this study, individuals with body-focused repetitive behaviors reported increased symptoms during the COVID-19 pandemic, highlighting the psychological impact of pandemic-related societal changes on this population.

This study found that the ID2 gene was highly expressed in bulge-derived keratinocytes when exposed to contact sensitizers and may serve as a marker to distinguish sensitizers from irritants during in vitro testing.

This review highlights the challenges in identifying histological features of adverse reactions to soft tissue fillers and emphasizes the need for increased awareness due to product uncertainty and delayed reactions.

In this study, researchers observed that atopic dermatitis may alter the appearance of allergic patch test reactions, demonstrating specific patterns like perifollicular erythema and yellowish areas that could aid in interpreting patch tests using dermoscopy, particularly in ambiguous cases.

This study found IL-17/IL-36 signaling to be predominant in both endotypes of Netherton syndrome, with distinct molecular profiles between NS-ILC and NS-SE lesions, offering potential therapeutic targets.

In this case report, a novel heterozygous mutation in the insulin receptor gene was identified in an adolescent girl with type A insulin resistance syndrome, characterized by excessive hair growth and skin changes, and her mother.

This study found no significant relationship between clinical markers of hyperandrogenism and lack of response to conventional antibiotic therapy in women with acne.

In this study, researchers identified significant signals indicating previously unrecognized risks of lipid metabolism abnormalities for several drugs, urging the need for better monitoring and label updates.

In this study, the elimination of NG2+ hair follicle stem cells during the anagen phase was associated with an aggravated sensitization phase of allergic contact dermatitis, suggesting their immunosuppressive role.

This study suggests that a novel computational method using side-effect data from social media might aid in drug repositioning by identifying known and potential therapeutic indications.

High-dose androgen therapy can help manage certain types of androgen resistance.

In this study, 19.6% of COVID-19 vaccine recipients reported post-vaccination mucocutaneous effects, mostly mild and self-limiting; the reactions were similarly frequent for Covishield and Covaxin.

This review discusses the roles of glucocorticoids and glucocorticoid receptors, and it explores potential genetic and non-genetic causes of glucocorticoid resistance or hypersensitivity syndromes, reporting no new clinical results.

Smart microneedles improve hair loss treatment by delivering drugs precisely with fewer side effects.

This study reported that classic anovulatory PCOS was the most common androgen excess disorder, followed by mild ovulatory PCOS and idiopathic hyperandrogenism, among patients evaluated for clinical hyperandrogenism.

This review discusses the use of contact hypersensitivity for alopecia areata and highlights its potential immunomodulatory benefits, but reports no new clinical findings.