research Treatment of Hirsutism by Finasteride and Flutamide in Women with Polycystic Ovary Syndrome
Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.
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research Proline-Rich Protein-Like PRPL1 Controls Elongation of Root Hairs in Arabidopsis Thaliana
A gene in Arabidopsis thaliana, AtPRPL1, affects root hair length but not cell wall composition.
research The Transdermal Inhibition of Melanogenesis by a Cell-Membrane-Permeable Peptide Delivery System Based on Poly-Arginine
A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.
research Effect of Finasteride on Behavioral Arousal and Somatosensory Evoked Potentials in Fetal Sheep
Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.
research Basics of Androgen Synthesis and Action
Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
research Side Effects of 5-Alpha Reductase Inhibitors: A Comprehensive Review
5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.
research Differential Diagnosis of Hyperandrogenism in Women with Polycystic Ovary Syndrome
The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
research Minoxidil: Right Atrial Cardiac Pathology in Animals and Humans
Minoxidil may cause heart issues in animals and humans.
research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Polycystic Ovarian Syndrome: Long-Term Health Consequences
Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.
research Divergent Neuroactive Steroid Responses to Stress and Ethanol in Rat and Mouse Strains: Relevance for Human Studies
Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.
research Alteration of Ethanol Drinking in Mice via Modulation of the GABAA Receptor with Ganaxolone, Finasteride, and Gaboxadol
Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.
research Pharmacotherapy of Polycystic Ovary Syndrome: An Update
New treatments for PCOS show promise, but no current medication treats all aspects of the condition.
research Treatment Strategies for Alopecia
Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.
research Cell Wall-Associated Root Hair Specific 10, a Proline-Rich Receptor-Like Kinase, Is a Negative Modulator of Arabidopsis Root Hair Growth
ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.
research Profile of the Progesterone Derivative Chlormadinone Acetate: Pharmacodynamic Properties and Therapeutic Applications
Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.
research Clinical and Hormonal Effects of the 5 Alpha-Reductase Inhibitor Finasteride in Idiopathic Hirsutism
Finasteride reduces hair growth and is safe for women with excessive hair.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research Dutasteride Reduces Alcohol’s Sedative Effects in Men in a Human Laboratory Setting and Reduces Drinking in the Natural Environment
Dutasteride makes alcohol less sedating and may lead to less drinking in men.
research The Frequency of Metabolic Syndrome Is Higher Among Brazilian Women With PCOS, Menstrual Irregularity, and Hyperandrogenism
Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.
research In Vivo Hair Growth Promotion Effects of Cosmetic Preparations Containing Hinokitiol-Loaded Poly(ε-Caprolactone) Nanocapsules
Cosmetics with hinokitiol-loaded nanocapsules were found to effectively promote hair growth.
research Antiandrogen Therapy in Dermatology
Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
research Becker's Nevus Associated with Chromosomal Mosaicism and Congenital Adrenal Hyperplasia
High androgen levels and genetic factors likely cause Becker's nevus and related symptoms.
research Cutaneous Lesions in Systemic Lupus Erythematosus
Skin problems are common in lupus, important for diagnosis, and can be triggered by sunlight.
research Autoimmune Polyendocrine Syndrome Type 1: An Italian Survey on 158 Patients
APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.
research Sex-Bias in COVID-19-Associated Illness Severity and Mortality in Cancer Patients: A Systematic Review and Meta-Analysis
Male cancer patients have a higher risk of severe illness and death from COVID-19 than female patients.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research New Steps Forward in the Neuroactive Steroid Field
Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
research Cardiovascular Risk Factors and Events in Women with Androgen Excess
Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.