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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

Erythropoietin helps hair grow and could be a potential treatment for hair loss.

Placental growth factor may help treat hair loss.

The studies identified key factors and potential treatments for skin and hair disorders.

Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.

VEGF helps squamous cell carcinoma grow in ways beyond just blood vessel formation.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

PRP could be a promising treatment for hair loss but needs more research.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Stopping methotrexate might reverse lymphoma-like conditions in some patients.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.

Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.

Rat dermal papilla cells have unique genes crucial for hair growth.

Activin activation in skin cells speeds up wound healing without affecting scar quality.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.

Wnt10b helps blood stem cells grow after injury.

New methods have greatly improved our understanding of stem cell behavior and roles in the body.

Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.

Robotic hair transplantation with AI offers more reliable, precise, and efficient hair restoration.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.