March 2013 in “Journal of pediatric nursing” This case report presents a 14-year-old girl with type A insulin resistance, illustrating diagnostic processes to differentiate it from type 2 diabetes in the context of pediatric obesity and hyperglycemia.
June 2021 in “Archives of Advances in Biosciences” This study suggests that finasteride at doses of 5 mg/kg BW or higher may adversely affect spermatogenesis and male fertility in NMRI mice.
7 citations
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March 2023 in “Gynecological Endocrinology” This study reported a rare case of ovarian steroid cell tumor removal resulting in normalized hormone levels, resumption of menstruation, and subsequent spontaneous pregnancy in a 31-year-old woman.
3 citations
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November 2021 in “Stress” This study found that school-related stress increases hair cortisol in girls and alters hair testosterone and cortisol levels in boys, indicating gender-specific hormonal responses to environmental changes.
2 citations
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November 2019 in “Case reports in women's health” In this study, two women with hyperandrogenic symptoms were found to have ovarian Leydig cell tumors after selective ovarian venous sampling and salpingo-oophorectomy, leading to a decline in testosterone levels post-surgery.
April 2020 in “Journal of the Endocrine Society” This case report highlights Leydig cell hyperplasia as a rare cause of increased testosterone and postmenopausal hirsutism, resolved after bilateral salpingo-oophorectomy in a 64-year-old woman.
17 citations
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December 2004 in “Bioorganic & Medicinal Chemistry Letters” This study identified N-acyl arylsulfonamides, particularly N-(Boc-piperidine-4-carbonyl)-benzenesulfonamides, as steroid sulfatase inhibitors with improved cellular potency compared to previous compounds.
1 citations
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August 2021 in “Canadian journal of neurological sciences” This article offers HTML content and a downloadable PDF but does not provide an abstract or new findings for summary.
119 citations
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November 2009 in “Human Reproduction” This study found that women with polycystic ovary syndrome have a higher prevalence of non-alcoholic fatty liver disease and increased androgen bioavailability may be involved alongside metabolic factors.
74 citations
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January 2011 in “Reproductive Biology and Endocrinology” This study suggests testosterone gel administered for one year to male chronic pain patients receiving morphine may improve sexual function and mental health, despite limited effects on overall pain scores.
35 citations
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December 2014 in “Clinical Obstetrics and Gynecology” This article discusses skin changes during pregnancy and emphasizes the importance of recognizing these physiological manifestations to prevent unnecessary tests and stress for pregnant patients; it reports no new study findings.
13 citations
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June 1989 in “Pediatric clinics of North America/The Pediatric clinics of North America” This article reviews assessment and management strategies for adolescent females with excessive hair growth and highlights the importance of evaluating potential androgen sources.
11 citations
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January 2017 in “Journal of Endocrinology/Journal of endocrinology” This study observed that female mice with disrupted 5α-reductase 1 showed increased insulin resistance and hepatic steatosis, suggesting altered glucocorticoid metabolism contributes to metabolic disorders.
2 citations
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September 2002 in “Journal of Endocrinological Investigation” The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.
November 2025 in “Healthcare” This study found that individuals with hair loss complaints had slightly lower zinc levels compared to controls, but the difference was clinically insignificant, suggesting zinc testing is not essential for diagnosing hair loss.
September 2024 in “International Journal of Molecular Sciences” This study found that administering a supraphysiological dose of testosterone to female rats significantly reduced estrogen and progesterone levels, disrupted sex steroid receptor expression, and interfered with the embryonic implantation window, indicating potential implications for androgen-related endometrial conditions.
July 2023 in “Endocrinology, diabetes & metabolism case reports” This case report involved a premenopausal woman with rapidly progressing virilizing symptoms caused by a rare sertoliform endometrioid carcinoma of the ovary. Following surgical intervention, her symptoms improved, highlighting the importance of recognizing virilizing symptoms as potential indicators of low-grade ovarian malignancies in similar cases.
April 2020 in “Journal of the Endocrine Society” This case report emphasizes the importance of early diagnosis of Swyer Syndrome in adolescents with slow pubertal progression and primary amenorrhea due to the high risk of germ cell cancers.
March 2026 in “The Journal of Sexual Medicine” In this study, older women aged 70 and above, treated for sexual dysfunction using carefully monitored hormone therapy, reported improvements in sexual function and symptom relief, with no incidences of cancer or thromboembolic events, though some experienced breast tenderness and hair changes.
This study found that switching juvenile mice from a high-fat, high-carbohydrate diet to a control diet optimally reduced hormonal imbalances and weight, with nutraceuticals offering partial support.
October 2024 in “Journal of the Endocrine Society” This case report highlights that in severe illnesses like sepsis, myxedema coma can occur with less elevated TSH levels than typical for primary hypothyroidism, likely due to inflammatory cytokines affecting TSH secretion, even when central lesions are absent.
November 2022 in “Journal of the Endocrine Society” This case study reports a rare instance of an estradiol-secreting adrenocortical carcinoma in a 58-year-old male, causing feminization and Marie-Antoinette syndrome, with potential paraneoplastic aortitis.
October 2024 in “Journal of the Endocrine Society” This case report highlights a patient with Ayme-Gripp syndrome, revealing an association between the syndrome and hypothyroidism, and underscores the importance of considering rare genetic conditions in differential diagnoses of endocrinopathies.
254 citations
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September 2014 in “Menopause” The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.
1 citations
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January 2018 in “Pediatrics in review” This case report describes a 7-year-old boy with medulloblastoma who developed central precocious puberty, potentially triggered by the mass effect of the tumor, which was managed with leuprolide.
855 citations
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June 2009 in “The Journal of Clinical Endocrinology & Metabolism” The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.
60 citations
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April 2003 in “Human Reproduction” This study found that Czech women with polycystic ovary syndrome in their thirties had a significantly worse cardiovascular risk profile compared to a control group, independent of obesity.
60 citations
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June 1997 in “Drugs & Aging” Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.
39 citations
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January 2004 in “Physiological Research” In this study, researchers reported that about one-third of men with premature alopecia displayed hormonal shifts and higher insulin resistance, resembling the prevalence pattern of PCOS in women.
26 citations
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February 2009 in “Drug Development Research” This article reviews the potential neuroprotective effects of 17α‐estradiol in neurodegenerative diseases and highlights its possibly lower toxicity compared to more feminizing hormones, but it reports no new clinical findings.