Ovarian Vein Sampling, and Serum and Urine Testosterone Monitoring in Ovarian Leydig Cell Tumors: A Report of Two Cases

November 2019 in “ Case reports in women's health ”

Grace Whiteley, Olivia Carpinello, Micah J. Hill, Alan H. DeCherney

ovarian Leydig cell tumors hyperandrogenism serum testosterone urine testosterone ovarian vein sampling testosterone hormone monitoring

TLDR Ovarian vein sampling helped diagnose rare ovarian tumors causing high testosterone, and surgery to remove the tumors lowered the testosterone levels.

The document reported on two cases of ovarian Leydig cell tumors in women with hyperandrogenism, where standard imaging failed to identify the tumors. Elevated serum and urine testosterone levels were key indicators, and selective ovarian vein sampling pinpointed the right ovarian tumors. Surgical removal led to a rapid decline in testosterone levels, confirming the diagnosis. The study underscored the importance of ovarian vein sampling and hormone monitoring in accurately diagnosing and managing these rare tumors.

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