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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Latanoprost can make eyelashes longer, thicker, and darker.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Finasteride with oral contraceptive helps improve hair loss in premenopausal women.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

No treatment fully prevents hair loss from chemotherapy yet.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

To manage diffuse hair loss, identify the cause, improve nutrition, remove triggers, and use specific treatments like minoxidil or finasteride.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Some common medications can harm male fertility, but many effects can be reversed.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Finasteride reduces hair growth better, but spironolactone has more side effects.

PCOS is a common hormonal disorder in women, treated with lifestyle changes and medications like hormonal contraceptives and metformin.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.