77 citations,
October 1986 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Nafarelin may effectively treat excessive hair growth in women by reducing certain hormone levels.
71 citations,
June 2006 in “Human Reproduction” Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.
68 citations,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
66 citations,
November 2001 in “European journal of endocrinology” Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.
58 citations,
November 2020 in “International Journal of Molecular Sciences” SHBG may be a useful early indicator and treatment target for PCOS.
53 citations,
January 1985 in “Acta obstetricia et gynecologica Scandinavica” Low-dose oral contraceptives reduced hair growth and testosterone levels in women with polycystic ovary syndrome.
52 citations,
May 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Parathyroid hormone-related protein helps control hair growth phases in mice.
44 citations,
July 2011 in “Dermato-endocrinology” Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.
39 citations,
September 2012 in “Human Reproduction” Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.
36 citations,
July 2011 in “Journal of The American Academy of Dermatology” People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.
35 citations,
December 2009 in “Human reproduction” Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.
34 citations,
March 2003 in “Veterinary Dermatology” Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.
33 citations,
January 2013 in “Dermatology” Over half of the adult women with acne in the study had higher than normal levels of male hormones, especially DHEA.
33 citations,
May 2006 in “Journal of Investigative Dermatology” PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.
32 citations,
March 2021 in “Journal of endocrinological investigation” Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.
30 citations,
October 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.
29 citations,
January 2006 in “Clinical chemistry and laboratory medicine” SHBG binding properties are unchanged in male liver cirrhosis patients.
29 citations,
September 1983 in “British Journal of Dermatology” Men with hair loss have lower SHBG and higher saliva testosterone levels, suggesting increased androgen activity.
28 citations,
January 2013 in “Journal of Thyroid Research” Thyroid hormone may speed up wound healing and hair growth, but more research is needed to understand its role in skin repair and use as a treatment.
27 citations,
October 1945 in “Endocrinology” Synthetic hormone treatment reduces melanin and hair growth in rats.
26 citations,
December 2006 in “Endocrinology” A cream with a specific hormone blocker increases hair growth in mice.
24 citations,
November 2015 in “Annals of Nutrition and Metabolism” Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.
24 citations,
September 2014 in “PloS one” Thyroid hormone receptors are essential for hair growth and wound healing.
24 citations,
July 2011 in “PubMed” Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.
23 citations,
April 1996 in “PubMed” Vitamin D3 and parathyroid hormone-related peptide may have important uses in skin treatments.
21 citations,
September 2021 in “Fertility and Sterility” A blood test level of 3.2 ng/mL of Antimüllerian hormone is good for identifying polycystic ovarian morphology in European women aged 25–45.
21 citations,
May 2005 in “Journal of the American Veterinary Medical Association” The exact cause of growth hormone-responsive alopecia in dogs is unclear.
20 citations,
September 2013 in “Anti-Cancer Drugs” PTH-CBD could help prevent and treat hair loss caused by chemotherapy in mice.
20 citations,
June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery” Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
18 citations,
May 1992 in “American Journal of Biological Anthropology” Higher androgen levels do not cause baldness in men.