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Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

Frizzled receptors are essential for various body development processes and maintaining certain body functions.

A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

PRX01, PRX44, and PRX73 are essential for root hair growth in Arabidopsis thaliana.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Whale genes show changes that help them live in water, like less hair and better flippers.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

A certain genetic variation is linked to a higher risk of polycystic ovarian syndrome.

Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.

A 66-year-old woman with skin lesions and other symptoms improved after treatment for porphyria cutanea tarda.

BcFLA1 protein is crucial for root hair growth in response to low phosphate in Brassica carinata.

The Asiatic lion has very low genetic diversity and unique genetic traits, highlighting the need for its conservation.

Two mutations in KRT74 and EDAR genes cause sheep to have finer wool.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

More research is needed to understand how testosterone is maintained in adult males.

Certain genetic variations in OCT1 may improve insulin sensitivity with metformin in women with PCOS.

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

A certain genetic variation in the IL1A gene may lower the risk of a hair loss condition in Chinese people.

New targeted immunotherapies are improving treatment for inflammatory skin diseases.

Shift work disrupts the body's natural clock, leading to health problems.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.