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This review provides an overview of the hairless gene in mice and humans, discussing its structure, expression, and implications for understanding skin physiology and human disorders related to gene disruption, but it reports no new empirical findings.

In this case report, lichen myxedematosus associated with hepatocellular carcinoma showed progressive improvement in skin lesions without further treatment following tumor resection.

This case report describes a 33-year-old woman with long-standing scalp issues and hair loss, revealing an unusual connection to past melanoma, but it presents no new research results.

This case report describes a 46,XY female patient with a novel homozygous nonsense mutation in the LHCGR gene, highlighting the need for molecular analysis in disorders of sexual development.

This study found that using dual-wavelength low-level laser therapy is more effective for hair regrowth in mice than single-wavelength treatment and significantly better than no treatment, based on 14 days of phototherapy with LED lights.

This study identified lymphatic vessels as crucial components of the hair follicle stem cell niche, coordinating connections and contributing to hair follicle regeneration in mice.

This study demonstrated that a 1-step, peroxidase-labeled conjugated antibody method provides more accurate immunoreactivity patterns in hair follicle substructures compared to the 2-step LSAB method, which may cause false-positive staining in sebaceous glands.

This study reports that the Luce LDS 100 infrared light therapy shows positive hair growth results after one year in men and women with androgenetic alopecia.

This study found that FDA-approved low-level light/laser therapy devices significantly increased hair density in individuals with pattern hair loss compared to sham devices.

This article describes a non-blinded study investigating low level laser therapy for seven patients but reports no new clinical findings.

This study reports that compound heterozygous loss-of-function mutations in the HEPHL1 gene in a child were associated with abnormal hair and cognitive issues, linking altered ferroxidase activity to hair disorders.

This review found that many low-level light therapy studies report beneficial effects but often fail to provide adequate measurement details, affecting the reliability and repeatability of the research.

This study suggests elevated homocysteine levels may serve as a biomarker for disease severity and vascular risk in cutaneous lupus erythematosus, indicating potential therapeutic benefits from B-vitamin supplementation and lifestyle changes.

This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.

This study suggests that human lymphoblastoid interferon, with or without prednisolone pretreatment, may be an effective and safe treatment option for hepatitis B in Oriental patients compared to placebo.

This study investigated the effects of heat-treated Limosilactobacillus fermentum LM1020 on hair growth and reported increased hair density, improved cellular activity, and beneficial scalp microbiota changes in patients with androgenetic alopecia over 24 weeks.

This study reported discovering a novel missense variant in a case of autosomal recessive woolly hair in a 31-year-old Chinese woman, which significantly reduced secretion of the encoded protein, likely leading to disease by impairing its hydrolytic function.

In this in silico study, researchers analyzed nonsynonymous SNPs in the LIPH gene linked to hypotrichosis and identified three potentially harmful variants (W108R, C246S, and H248N) out of 215 total, using sequence- and architecture-based bioinformatics techniques to differentiate between harmful and benign SNPs.

This study found that long-hair follicular unit excision for hairline restoration resulted in high patient satisfaction, with a 93% graft survival rate and improved quality of life scores postoperatively.

This study identified two prevalent and one newly proposed founder LIPH mutations in Japanese patients with autosomal recessive woolly hair/hypotrichosis and associated these mutations with different severities of hair loss.

In this study, transgenic mice with a truncated latent transforming growth factor-beta-binding protein showed reduced keratinocyte proliferation and alterations in the hair cycle due to mis-localization of transforming growth factor-beta.

This study demonstrated that lactate dehydrogenase activity is notably high in quiescent hair follicle stem cells within mouse skin using a specific enzymatic activity assay.

This study found that low-level laser therapy (LLLT) may enhance hearing recovery after noise-induced hearing loss in rats.

This study suggests that the harlequin ichthyosis mouse model closely resembles human type 2 harlequin ichthyosis, indicating its potential as a useful model for studying the human condition.

This study suggested that differences in hair follicle development, indicated by the frequency of underdeveloped hairs, significantly contribute to the variation in hair loss severity among Japanese individuals with the LIPH c.736T>A mutation.

This review discusses photobiomodulation as a potential treatment for hair loss, highlighting its safety and possible effectiveness but noting cost, protocol standardization, and expectation management as limitations; it reports no new clinical results.

This study found that in lichen planopilaris, the basement membrane zone of the hair follicles exhibited disrupted and discontinuous staining patterns, potentially contributing to scarring and irreversible hair loss.

This pilot study explored a new method using laser-capture microdissection and 16S rRNA gene sequencing to analyze the human scalp hair follicle microbiome more accurately, revealing region-specific variations in microbial diversity and abundance.

This review discusses the evolution and potential of photobiomodulation therapy, highlighting its transition from skepticism to recognition in medical research; it reports no new experimental findings.

This study provides evidence that ILC1-like cells can induce alopecia areata in previously healthy human hair follicles, challenging the view that it is solely an autoantigen-dependent autoimmune disease.