Lichen Myxedematosus in a Patient with Hepatocellular Carcinoma

    August 2000 in “ British Journal of Dermatology
    Pang‐Kuo Lo, T.Y. Tzung
    Studysummary In this case report, lichen myxedematosus associated with hepatocellular carcinoma showed progressive improvement in skin lesions without further treatment following tumor resection.
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    Lichen myxedematosus (LM) is a rare skin disorder characterized by waxy papules and skin thickening, often associated with monoclonal paraproteinaemia. In a reported case, a 50-year-old male with LM and hepatocellular carcinoma (HCC) experienced skin lesions and diminished hair growth. Following the surgical removal of a liver tumor, the patient's skin lesions improved, and eyebrow hair regrew without further treatment. Despite the surgery, the patient's polyclonal gammopathy remained largely unchanged. This case suggested a potential link between LM and HCC, with tumor resection leading to symptom improvement.
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