Lichen Myxedematosus in a Patient with Hepatocellular Carcinoma
August 2000
in “
British Journal of Dermatology
”
Studysummary In this case report, lichen myxedematosus associated with hepatocellular carcinoma showed progressive improvement in skin lesions without further treatment following tumor resection.
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Lichen myxedematosus (LM) is a rare skin disorder characterized by waxy papules and skin thickening, often associated with monoclonal paraproteinaemia. In a reported case, a 50-year-old male with LM and hepatocellular carcinoma (HCC) experienced skin lesions and diminished hair growth. Following the surgical removal of a liver tumor, the patient's skin lesions improved, and eyebrow hair regrew without further treatment. Despite the surgery, the patient's polyclonal gammopathy remained largely unchanged. This case suggested a potential link between LM and HCC, with tumor resection leading to symptom improvement.