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      Interventions for Alopecia Areata

      research Interventions for alopecia areata

      164 citations , April 2008 in “Cochrane library”
      This review of interventions for alopecia areata found no significant treatment benefits for hair growth compared to placebo, indicating a need for larger, well-conducted studies.
      Decreased Serum Ferritin Is Associated With Alopecia in Women

      research Decreased Serum Ferritin is Associated With Alopecia in Women

      163 citations , November 2003 in “Journal of Investigative Dermatology”
      This study found that women with androgenetic alopecia or alopecia areata have significantly lower serum ferritin levels than those without hair loss, suggesting a potential link between these types of alopecia and decreased iron stores.
      Probing the Effects of Stress Mediators on the Human Hair Follicle

      research Probing the Effects of Stress Mediators on the Human Hair Follicle

      159 citations , November 2007 in “American Journal of Pathology”
      In this study, researchers found that substance P triggered premature catagen development and immune changes in human scalp hair follicles, providing a possible biological link between stress and hair loss conditions like telogen effluvium and alopecia areata.
      Lichen Planus

      research Lichen planus

      155 citations , June 2009 in “International Journal of Dermatology”
      This extensive review discusses the clinical manifestations, potential associations, and treatment approaches for lichen planus, but reports no new clinical results, highlighting gaps in evidence for therapeutic strategies.
      Alopecia Areata: Overview and Treatment Options

      research Alopecia areata

      151 citations , February 2007 in “International Journal of Dermatology”
      This review explores the causes and mechanisms of alopecia areata and discusses current treatments, reporting no new clinical findings.
      An Update on Congenital Adrenal Hyperplasia

      research An Update of Congenital Adrenal Hyperplasia

      151 citations , December 2004 in “Annals of the New York Academy of Sciences”
      This review discusses nonclassical 21-hydroxylase deficiency as the most common autosomal recessive disorder in humans and highlights the effectiveness of glucocorticoid treatment in reversing related symptoms.
      Clinical Manifestations of Cutaneous Lupus Erythematosus

      research Clinical manifestations of cutaneous lupus erythematosus

      148 citations , February 2005 in “Autoimmunity Reviews”
      This article discusses the distinct skin findings associated with lupus erythematosus, noting that some are specific to lupus while others are nonspecific and occur with various diseases; it reports no new results.
      The Immune Functions of Keratinocytes in Skin Wound Healing

      research The Immune Functions of Keratinocytes in Skin Wound Healing

      147 citations , November 2020 in “International Journal of Molecular Sciences”
      This review discusses the immune roles of keratinocytes in wound healing and chronic wound inflammation, emphasizing their potential impact on chronic wound pathology and highlighting areas for future research.
      Epidemiology and Burden of Alopecia Areata: A Systematic Review

      research Epidemiology and burden of alopecia areata: a systematic review

      144 citations , July 2015 in “Clinical, Cosmetic and Investigational Dermatology”
      This review reports that alopecia areata affects about 2% of people globally and is linked with psychiatric and medical comorbidities, highlighting its significant disease burden.
      Lupus Erythematosus: Systemic and Cutaneous Manifestations

      research Lupus erythematosus: systemic and cutaneous manifestations

      144 citations , September 2006 in “Clinics in Dermatology”
      This article outlines manifestations of systemic lupus erythematosus, noting rapid joint symptom improvement with corticosteroids and antimalarial drug responsiveness for skin symptoms, and links anti-Ro with photosensitive rash and subacute lupus.
      Human Skin Stem Cells and the Aging Process

      research Human skin stem cells and the ageing process

      143 citations , September 2008 in “Experimental gerontology”
      This review discusses the diverse roles and characteristics of epidermal and dermal stem cells in skin regeneration and aging, highlighting their potential applications in regenerative medicine and reports no new clinical results.
      Dermatological Adverse Events with Taxane Chemotherapy

      research Dermatological adverse events with taxane chemotherapy

      141 citations , September 2016 in “European Journal of Dermatology”
      This review examines dermatological side effects of taxane chemotherapy reported in past studies and highlights the necessity for identifying and managing these conditions to maintain cancer patients' quality of life; it presents no new clinical results.
      Exosomes for Repair, Regeneration, and Rejuvenation

      research Exosomes for repair, regeneration and rejuvenation

      135 citations , December 2015 in “Expert Opinion on Biological Therapy”
      This review synthesizes recent research on exosomes, highlighting their role as key modulators in regenerative outcomes and suggesting they may offer advantages over stem cell-based therapies in process and regulation.
      Androgenetic Alopecia and Microinflammation

      research Androgenetic alopecia and microinflammation

      131 citations , August 2000 in “International Journal of Dermatology”
      Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
      Cutaneous Manifestations of Systemic Lupus Erythematosus

      research Cutaneous manifestations of systemic lupus erythematosus

      127 citations , September 1996 in “British Journal of Dermatology”
      This study found that cutaneous signs such as chilblains and urticaria were notably common in British patients with systemic lupus erythematosus, while subacute cutaneous lesions were less frequent.
      Targeting the Janus Kinase Family in Autoimmune Skin Diseases

      research Targeting the Janus Kinase Family in Autoimmune Skin Diseases

      124 citations , October 2019 in “Frontiers in Immunology”
      This review discusses the role of the JAK-STAT pathway in autoimmune skin diseases and suggests potential therapeutic benefits of JAK inhibitors, but reports no new experimental results.
      Dermatologic Changes Associated With Interleukin 2 Administration

      research Dermatologic Changes Associated With Interleukin 2 Administration

      123 citations , September 1987 in “JAMA”
      This study observed that patients receiving IL-2 immunotherapy developed a skin eruption characterized by burning and pruritus, which resolved shortly after stopping the infusion, suggesting that IL-2 mediated these effects.
      Alopecia Areata: Pathogenesis And Treatment

      research Alopecia areata: Pathogenesis and treatment

      122 citations , November 1984 in “Journal of the American Academy of Dermatology”
      This review discusses the potential autoimmune pathogenesis and various contributing factors of alopecia areata, noting that current treatments remain palliative while emerging therapies offer new hope for extensive cases.
      Extraskeletal Actions of Vitamin D

      research Extraskeletal actions of vitamin D

      119 citations , July 2016 in “Annals of the New York Academy of Sciences”
      This review examines the impact of vitamin D signaling in extraskeletal tissues and notes that expected benefits from animal and cell studies have not been consistently replicated in human clinical trials.
      Drug-Induced Skin, Nail, and Hair Disorders

      research Drug-Induced Skin, Nail and Hair Disorders

      114 citations , January 2007 in “Drug Safety”
      This review discusses various adverse drug reactions affecting the skin, hair, and nails, emphasizing the importance of recognizing and reporting these reactions but reports no new clinical findings.