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Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Plant-based ingredients are effective and safe for modern skincare products.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.

St. John's Wort can cause dangerous high blood pressure if taken with certain foods.

More pediatric-specific research and guidelines are needed to improve hidradenitis suppurativa treatment in children and adolescents.

A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Mesotherapy shows promise for cellulite and facial rejuvenation but has mixed results for body sculpting and hair loss, with more research needed for safety and effectiveness.

Dieckol from Ecklonia cava may help hair growth and could be a potential hair loss treatment.

Skin problems like itching, dry skin, and hair loss are more common in hepatitis C patients after interferon treatment, but lichen planus is not linked to the infection.

Antimicrobial therapy can help manage Folliculitis Decalvans.

New hair and skin changes were found in a rare case of syphilis-related hair loss.

Pannexin 3 is important for bone formation and the development of bone cells.

Black women's unique hair characteristics and styling practices can lead to specific scalp conditions, which require early diagnosis and appropriate treatment.

The document concludes that recognizing oral lesions is important for diagnosing syphilis.

Peginterferon alfa-2b and ribavirin therapy for hepatitis C can cause serious side effects, some different from those reported in clinical trials.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Skin problems can be linked to sexual abuse, requiring careful medical and psychological evaluation.

Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.

The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.

3D-printed mesoporous scaffolds show promise for personalized drug delivery with controlled release.

The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.