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    Did you mean Histone Modifications?
    Glossary Histone Modifications

    chemical changes to histone proteins that regulate gene expression

    Histone modifications refer to chemical changes made to histone proteins, which help package DNA in the cell nucleus. These modifications, such as methylation or acetylation, can influence gene expression by either tightening or loosening the DNA around histones, thereby controlling access to genetic information. This process is crucial for regulating various biological functions and can impact conditions like alopecia by affecting the genes involved in hair growth.

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    1. Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced Differentiation PLoS ONE · 2007 · 98 citations
    2. Noval advance of histone modification in inflammatory skin diseases and related treatment methods Frontiers in immunology · 2024
    3. Mettl3-catalyzed m <sup>6</sup> A regulates histone modifier and modification expression in self-renewing somatic tissue Science Advances · 2023 · 24 citations
    4. Genome-wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage Cell stem cell · 2011 · 191 citations
    5. Abnormal epigenetic modifications in peripheral blood mononuclear cells from patients with alopecia areata British Journal of Dermatology · 2011 · 48 citations
    6. Glucose metabolism regulates expression of hair-inductive genes of dermal papilla spheres via histone acetylation Scientific reports · 2020 · 6 citations
    7. Epigenetic control of adult stem cell function Nature Reviews Molecular Cell Biology · 2016 · 179 citations
    8. The Immune Functions of Keratinocytes in Skin Wound Healing International Journal of Molecular Sciences · 2020 · 147 citations
    9. Cell fate decisions: emerging roles for metabolic signals and cell morphology EMBO Reports · 2017 · 100 citations
    10. Stiffness-Controlled Thermoresponsive Hydrogels for Cell Harvesting with Sustained Mechanical Memory Advanced Healthcare Materials · 2017 · 22 citations
    11. Defining the identity of mouse embryonic dermal fibroblasts Genesis · 2016 · 21 citations
    12. Epigenetic regulation in adult stem cells and cancers Cell & Bioscience · 2013 · 20 citations
    13. Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of <i>Foxn1</i> in Thymic Epithelial Cells 2019 · 17 citations
    14. Tailored chromatin modulation to promote tissue regeneration Seminars in Cell & Developmental Biology · 2019 · 10 citations
    15. sPLA2-IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation Stem cells · 2016 · 9 citations
    16. Transcriptional regulation of the thymus master regulator <i>Foxn1</i> Science immunology · 2022 · 6 citations
    17. Epigenetics and Other Autoimmune Skin Diseases Elsevier eBooks · 2015 · 2 citations
    18. H3K4me3 regulates the transcription of RSPO3 in dermal papilla cells to influence hair follicle morphogenesis and development Epigenetics & Chromatin · 2025 · 1 citations
    19. The role of epigenetics in the pathogenesis of cutaneous diseases: a comprehensive review International Journal of Research in Medical Sciences · 2026
    20. Pediatric Endocrine-Disrupting Chemical Exposure Produces Irreversible Organizational Injury: Biomarker Evidence Necessitating a Precautionary Public Health Framework Scholarly review . · 2026
    21. H3K9me3 controls epidermis morphogenesis by regulating RNA Pol II dynamics at developmental promoters and enhancers Nature Communications · 2026
    22. Epigenetic and Environmental Regulation of Skin Appendage Regeneration 2015
    23. Epigenetic and transcriptional profiling of secondary hair follicle stem cells during cashmere growth Scientific Data · 2026
    24. Epigenetic Mechanisms, Assessment and Therapeutics of Epidermal Stem Cells in Skin Aging Stem Cells International · 2025
    25. Dynamics and Epigenetics of the Epidermal Differentiation Complex Epigenomes · 2024
    26. Targeting the hallmarks of aging: preclinical evidence and molecular mechanisms underlying the therapeutic potential of Centella asiatica (L.) Urban Journal of Biological Studies · 2026
    27. Committing to a Hairy Fate: Epigenetic Regulation of Hair Follicle Stem Cells Cell stem cell · 2011 · 5 citations
    28. Hairless: A nuclear receptor corepressor essential for skin function Advances in developmental biology · 2006
    29. Tumores "borderline" de músculo liso del útero Clínicas obstétricas y ginecológicas de Norteamérica · 2006 · 1 citations
    30. Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins Scientific reports · 2018 · 54 citations