January 2025 in “Investigative and Clinical Urology” This study found that after 12 weeks of taking the trial product SHPro®, participants reported improvements in prostate symptom scores and erectile function, with confirmed safety.
3 citations
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January 2019 in “Therapeutic advances in urology” This review concluded that WS PRO 160 I 120 mg, a herbal preparation, may be an effective and safer alternative to standard drugs for treating lower urinary tract symptoms in men with benign prostatic hyperplasia.
September 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This article is a promotional piece about the MaasaLong supplement, which is claimed to improve male health concerns like erectile dysfunction, with no new empirical research results reported.
March 2026 in “Canadian Urological Association Journal” This study observed that complementary and alternative medicine, often marketed to men as ways to enhance "optimization," "recovery," and "vitality," has become mainstream, with many believing in its benefits for testosterone, erections, libido, hair loss, and sperm quality.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This piece describes the EndoPump Male Enhancement supplement, which claims to enhance erections and libido, but notes that there is insufficient medical evidence supporting the efficacy of its ingredients for sexual health.
2 citations
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June 2023 in “Journal of the American Academy of Dermatology” This observational study using NHANES data from 2011 to 2020 found that the use of hair, skin, and nails supplements almost doubled, particularly among younger, female, Black, and Hispanic/Latino individuals, despite limited evidence on their efficacy and potential health risks.
January 2025 in “Indian Journal of Animal Research” This study observed that herbal feed supplementation in Frieswal breeding bulls improved semen volume and motility, while significantly lowering dihydrotestosterone levels, suggesting a potential mechanism for enhancing semen quality.
4 citations
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October 2020 in “Toxicology Mechanisms and Methods” This study found that in male rats, hesperidin co-administration ameliorated finasteride-induced testicular toxicity by reducing oxidative stress and improving antioxidant status, sperm parameters, and enzyme activity compared to finasteride treatment alone.
February 1999 in “Drugs in R & D” The document concludes that various drugs for men's health issues are in development, with treatments for sexual dysfunction and prostate conditions being the most advanced.
4 citations
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October 2023 in “Fertility and Sterility” This review highlights potential negative impacts of certain medications on male fertility, such as hormonal disruption and germ cell toxicity, emphasizing the importance of clinicians being aware of these effects to advise on safer alternatives.
September 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This article discusses the MaasaLong male enhancement supplement, which claims to improve erectile dysfunction and overall male health but provides no new empirical results.
150 citations
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February 2008 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study suggests that antiandrogens may slightly reduce hirsutism severity compared to placebo, but evidence is weak and their relative efficacy remains uncertain.
January 2026 in “Food and Nutrition Sciences” This randomized, placebo-controlled trial reported that USPlus PRO saw palmetto extract significantly improved lower urinary tract symptoms, including voiding, incomplete emptying, and weak stream, as well as sexual function in males over 12 weeks, while maintaining a favorable safety profile.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This article reviews the benefits of Truman Plus Male Enhancement for testosterone levels and sexual health, but it does not present any new clinical study results.
October 2025 in “International Journal of Innovative Research in Technology” This review examines the evidence on nutritional and herbal supplements for women's health, emphasizing the need for more long-term studies to develop evidence-based guidelines for personalized supplementation.
September 2017 in “Springer eBooks” This paper reports that certain supplements, particularly whey protein isolate, growth hormones, and anabolic precursors, have a significant negative effect on hair loss.
8 citations
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November 2015 in “Saudi Journal of Biological Sciences” This study found that KH053, combining Panax ginseng and bee-pollen, significantly reduced prostate weight and DHT levels, inhibiting BPH development in a rat model.
2 citations
,
November 2021 in “International Journal of Current Pharmaceutical Research” This review discusses the pathogenesis, causes, and treatments of hirsutism but provides no new clinical findings; the authors emphasize the strong impact of hirsutism on quality of life.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, Saw Palmetto at a physiological dose partially inhibited 5-α-reductase and improved hormonal balance, inflammation, and mitochondrial function, with synergy observed when combined with Lycopene, L-Arginine, and Astaxanthin, enhancing male prostatic and endocrine health without endocrine side effects.
3 citations
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June 2012 in “Korean Journal of Human Ecology” This study found that a supplement containing medicinal plant extracts, amino acids, and vitamins decreased hair loss and increased hair thickness over three months, without significant side effects, in participants with hair loss concerns.
September 2022 in “Dermatologic Therapy” This study found that the U.S. stock market responded heterogeneously to the latest presidential elections, with positive reactions in the Energy, Financials, and Industrials sectors but poorer performance among firms with better environmental scores.
January 2012 in “Surgical & Cosmetic Dermatology” This study found that a dietary supplement improved hair strength and shine in participants with hair damage from breakage.
2 citations
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May 2021 in “Journal of pharmaceutical and biomedical analysis” This study utilized a UHPLC-HRMS method to identify eight active pharmaceutical ingredients, such as ketoconazole and minoxidil, in 26 out of 100 analyzed cosmetic products.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study reported that Saw Palmetto, at a physiological dose, partially inhibits 5-alpha-reductase and, when combined with Lycopene, L-Arginine, and Astaxanthin, demonstrates a synergistic effect in restoring hormonal balance, reducing inflammation, and improving hair density, urinary flow, and oxidative biomarkers in related male health conditions.
This study found that consumption of dietary supplements and sports nutrition may lead to therapeutic and cosmetic improvements, benefiting skin, hair, and nails while potentially enhancing athletic performance.
2 citations
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January 2023 in “Uro” This study found that both a proprietary ultrahigh-pressure extract and a hexanic extract of saw palmetto showed comparable inhibition of 5α-reductase, suggesting similar potential for managing symptoms of benign prostatic hyperplasia.
4 citations
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June 1990 in “Postgraduate medicine” This review highlights that pharmacologic therapy for hirsutism can effectively decrease hair growth, normalize menstrual cycles, and reduce endometrial cancer risk, with improvements in physical and mental well-being and minimal serious side effects reported.
1 citations
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June 2010 in “Mayo Clinic Proceedings” This article reviews the Clinical Pearls presentation format introduced at the American College of Physicians' 2001 meeting for its effectiveness in applying practical clinical tips, but provides no new empirical results.
December 2023 in “̒Ulūm-i dārūyī” This review provides a comprehensive examination of the causes and treatments for hirsutism in women, highlighting the role of pharmacological therapies and novel nanotechnology-based methods in improving patient quality of life.
April 2026 in “Journal of Natural Remedies” This review presents a comprehensive evaluation of eleven traditional herbs, detailing their phytochemical properties, mechanisms, pharmacokinetics, and potential roles in managing alopecia, positioning them as holistic alternatives to conventional treatments like minoxidil and finasteride.