Nutritional Pharmacology and Mechanistic Insights of Saw Palmetto in Male Endocrine and Prostatic Disorders
November 2025
in “
Zenodo (CERN European Organization for Nuclear Research)
”
TLDR Saw Palmetto, combined with Lycopene, L-Arginine, and Astaxanthin, improves male health by balancing hormones, reducing inflammation, and enhancing hair and urinary health without side effects.
This study explores the role of Saw Palmetto as a systems-level modulator in male endocrine and prostatic disorders, integrating it with Lycopene, L-Arginine, and Astaxanthin within the Keyora framework. At a physiological dose, Saw Palmetto partially inhibits 5-alpha-reductase, reduces inflammatory markers, and enhances mitochondrial bioenergetics. The combination with other compounds creates a tri-axis synergy that restores hormonal balance, suppresses chronic inflammation, and improves microvascular oxygenation. Clinical data show benefits such as enhanced hair density, improved urinary flow, and reduced oxidative and inflammatory biomarkers, without adverse endocrine effects, suggesting a shift from symptomatic treatment to a holistic approach in male health management.
