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This narrative review found a strong association between oxidative stress and the severity of alopecia areata, noting that increased oxidant and reduced antioxidant biomarkers correlate with higher disease severity scores, and emphasizes the need for larger prospective studies for clinical validation.

This study found that linoleic acid may help protect against acrylamide toxicity in female albino rats.

This study found that individuals with premature hair graying had significantly lower levels of antioxidants compared to controls, but the severity of graying did not significantly correlate with oxidative stress levels.

This study found that ischemia-modified albumin (IMA) may be a promising biomarker of oxidative stress in patients with alopecia areata, offering better potential compared to other oxidative stress markers.

This research studied European human hair, finding that cysteic acid and protein carbonylation increased with both chemical and photochemical oxidation. Protein carbonylation was highlighted as a more sensitive marker for photochemical oxidation, providing better in situ visualization of hair damage than cysteic acid.