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The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

New drugs for heart disease may be developed from molecules secreted by stem cells.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Testosterone replacement therapy should be used for men with low testosterone levels and symptoms of hypogonadism, after careful diagnosis and considering individual needs.

3D cell-derived matrices improve tissue regeneration and disease modeling.

Changing the diagnosis criteria for PCOS might miss women at risk for related health issues.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

Hair color and length affect metabolite profiles in hair, so they should be considered in hair analysis.

New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.

Antiandrogens are the main treatment for hirsutism, with individualized care and safe, affordable options needed.

Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Breast cancer may be detectable through changes in scalp hair lipids.

The document concludes that diagnosing PCOS requires a thorough approach, considering various symptoms and risks, and calls for improved methods to identify PCOS types and prevent diabetes.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

The document suggests new ways to assess and diagnose hyperandrogenism to improve accuracy.

The polyherbal hair oil effectively treats various hair problems and promotes hair health.

Herbal hair oil made with natural ingredients helps reduce hair loss, dandruff, and graying.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

The VCO-based herbal hair tonic is effective, safe for hair loss treatment, and can be mass-produced.

Ancient hair can preserve hormones, revealing health and fertility insights.

The document concludes that effectively managing PCOS requires a multifaceted approach.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.

People with Parkinson's disease have higher levels of cortisone in their hair, which may indicate chronic stress hormone dysfunction.

Scientists successfully edited a goat's genes to grow more and longer cashmere hair.