research Hypotensive Activity and Toxicology of Constituents from Bombax Ceiba Stem Bark
Bombax ceiba stem bark extracts can lower blood pressure, but high doses can be toxic and lethal.
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research Cronkhite-Canada Syndrome: A Rare Disease Presenting with Dermatological and Gastrointestinal Manifestations
A patient with Cronkhite-Canada syndrome improved with nutritional support and steroids, but early diagnosis is key due to high mortality.
research Toxic Epidermal Necrolysis: A Review of Etiology, Diagnosis, and Management
Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.
research Coinfection of Secondary Syphilis, Condyloma Acuminata, and Human Immunodeficiency Virus (HIV) in a Homosexual Man
A 22-year-old homosexual man was diagnosed with secondary syphilis, genital warts, and HIV, highlighting the high STI risk in men who have sex with men.
research Reporting on Adverse Clinical Events
The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.
research Menopausal Androgen Excess-Associated Cardio-Metabolic Risk: Clues for Ovarian Leydig Cell Tumor (Case Report and Mini-Review of Literature)
High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.
research Nonpigmented Hair Removal Using Photodynamic Therapy in Animal Model
Photodynamic therapy can remove nonpigmented hair in mice and might work for humans.
research Acne
Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
research Postmenopausal Hyperandrogenism Due to Ovarian Hyperthecosis
A woman's high testosterone levels and related symptoms improved after ovary removal surgery.
research Clinical Aspects of the Metabolic Syndrome
Losing weight and eating better are key to managing metabolic syndrome and its related conditions.
research Necrolytic Migratory Erythema in a Cat with Glucagonoma Syndrome
A cat with a rare pancreatic tumor and diabetes died despite treatment, showing similar symptoms to a human condition.
research Acne Vulgaris
Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.
research Diagnostic Approach to the Pruritic Cat
Finding the cause of a cat's itchiness requires a careful process and good communication with the owner.
research Flavonoids and Saponins: What Have We Got or Missed?
More high-quality research is needed to recommend flavonoids and saponins for clinical use.
research The IVIG Treatment Response in Autoimmune Polyendocrine Syndromes Type 2 with Anti-GAD65 Antibody-Associated Stiff Person Syndrome: A Case Report and Literature Review
IVIG therapy significantly improved symptoms in a patient with APS-2 and SPS.
research Rare Diagnosis of a Proliferating Pilar Tumor in a Facial Hairline Cyst
The lump on a woman's scalp was a rare, potentially cancerous tumor from the hair follicle, not a common cyst.
research Adult Kawasaki's Disease with Myocarditis, Splenomegaly, and Highly Elevated Serum Ferritin Levels
Kawasaki's disease can occur in adults and should be considered with specific symptoms and high ferritin levels.
research Ovarian Vein Sampling, and Serum and Urine Testosterone Monitoring in Ovarian Leydig Cell Tumors: A Report of Two Cases
Ovarian vein sampling helped diagnose rare ovarian tumors causing high testosterone, and surgery to remove the tumors lowered the testosterone levels.
research A Rare Cause of Postmenopausal Hyperandrogenism
A 71-year-old woman developed male-like features due to high testosterone levels caused by a benign ovarian tumor, which was successfully removed by surgery.
research A Case of Systemic Mastocytosis: An Ultrastructural and Immunohistochemical Study of Dermal Mast Cells in Relation to Activation of the Epidermal Melanin Unit
Prednisone reduces organ mast cell infiltration but does not alter the abnormal appearance of mast cells in systemic mastocytosis.
research Hyperandrogenism, Elevated 17-Hydroxyprogesterone and Its Urinary Metabolites in a Young Woman with Ovarian Steroid Cell Tumor, Not Otherwise Specified: Case Report and Review of the Literature
A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.
research The Impact of HIV-Related Diseases on Pigmented Skin Types
HIV can cause skin disorders, which are often the first sign of infection, especially in people with darker skin.
research Management of Autoimmune-Associated Alopecia Areata
Treatments for autoimmune hair loss have limited success and often relapse, and emotional support is crucial for those affected.
research Management of Autoimmune-Associated Alopecia Areata
Treatments for autoimmune hair loss have limited success and patients need emotional support and self-acceptance.
research Histopathology of the Alopecias
Examining scalp tissue under a microscope helps diagnose and understand hair loss diseases.
research Lipoatrophy and Severe Metabolic Disturbance in Mice with Fat-Specific Deletion of PPARγ
Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
research The Pharmacology of Methotrexate
Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.
research The Histopathologic Spectrum of Psoriasis
Psoriasis skin changes are complex and might need several biopsies for a clear diagnosis.
research Tinea Capitis: An Overview with Emphasis on Management
New antifungal treatments for a children's scalp infection are effective and safe, but it's not decided if they will become the preferred option over the old treatment.
research Safety Profile of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors: A Disproportionality Analysis of FDA Adverse Event Reporting System
EGFR-TKIs can cause significant skin, nail, and organ side effects.