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This study describes the first case of female pseudohermaphroditism due to a novel homozygous glucocorticoid receptor gene mutation, indicating possible pre- and postnatal virilization in affected females.

This study reports a case of GGCX syndrome in a 55-year-old Japanese male, characterized by PXE-like symptoms and coagulation deficiency, with an unreported phenotype of possible spinocerebellar degeneration.

This article reviews recent advances in the synthesis of oxasteroids and reports no new experimental results.

This paper describes recent advancements in the synthesis of thiasteroids but reports no new experimental results, noting that introducing heteroatoms in steroidal structures has potential biological effects.

This study suggests that 5alpha-dihydroprogesterone could be an effective, non-sedative anticonvulsant for drug-resistant complex partial seizures, as observed in a rat model.

This review provides an overview of the hairless gene in mice and humans, discussing its structure, expression, and implications for understanding skin physiology and human disorders related to gene disruption, but it reports no new empirical findings.

In this study, the researchers developed a quantum algorithm, QuantAnts machines, which identified complexes of CD9, CD34, and CD74 as potential targets for certain cancers involving the RAS pathway.

This case report highlights the use of microarray analysis to identify cryptic chromosomal rearrangements in a young woman with intellectual disability and multiple congenital anomalies.

In this study, researchers observed that twins with a novel de novo nonsense variant in HRAS exhibited distinctive features, including neuropsychiatric symptoms, potentially indicating a wider clinical spectrum for conditions known as RASopathies.

This review examines the physiological, biochemical, and molecular mechanisms by which DHEA and DHEA-S influence various bodily systems, citing rodent studies, but presents no new clinical results.

In this study, specific genetic polymorphisms in the KRT71 gene were associated with hairless and curly phenotypes in Sphynx and Devon Rex cats.

Hhip-Cre effectively targets dermal papilla cells for gene manipulation in hair biology.

This study found that 11α-hydroxyprogesterone is a potent inhibitor of 11βHSD2 in vitro and may serve as a precursor to unique C11α-hydroxy steroids in prostate cancer tissue.

This review discusses diosgenin's potential benefits for several chronic diseases and emphasizes extraction and quantification techniques, but reports no clinical findings.

This research explored methods to obtain transgenic sheep embryos expressing synthetic spider silk genes in hair follicles using somatic cell nuclear transfer, with successful in-vitro development observed.

Hair follicle dermal stem cells help control hair growth timing by regulating signals at the hair germ–dermal papilla interface.

In this study, researchers used conditional mouse models to show that inactivation of the Alx4 gene in specific cell lineages leads to craniofacial and limb defects without affecting postnatal survival, providing insights into Alx4's role in development and disease.

This study describes a new imaging platform for the adult Drosophila midgut, facilitating real-time observation of cell behaviors and dynamics involved in organ renewal.

This study demonstrated that a mechanical-assisted post-bioprinting strategy significantly increased cell numbers and enhanced regenerative capabilities in hollow hydrogel-based scaffolds for bone defect repair in vivo.

This study identified enzymes responsible for regulating androgen action in the human prostate, suggesting that inhibiting AKR1C2 or RL-HSD may have therapeutic potential in androgen insufficiency or benign prostatic hyperplasia, respectively.

This study revealed the complex three-dimensional innervation of touch domes in cat forepaw skin, highlighting the extensive branching and unmyelinated endings associated with Merkel cell–axon complexes.

This study found that the synthesized compound 7b exhibited higher 5α-reductase inhibitory activity, increased solubility, and dissolution compared to finasteride, suggesting its potential as a lead compound for benign prostatic hyperplasia treatment.

This study developed and validated a highly sensitive method using ultrahigh-performance liquid chromatography with tandem mass spectrometry for accurately analyzing nine neuroactive steroids in human serum, which could enhance understanding of disease pathophysiology and support new biomarker and therapeutic discovery.

In this prospective phase II clinical trial, researchers are investigating whether adding dutasteride to combined androgen blockade can improve the response rate and clinical outcomes for patients with androgen receptor-positive recurrent or metastatic salivary duct carcinoma.

The researchers reported that during early embryogenesis and larval development in Silurana tropicalis, inhibiting steroidogenic enzymes cyp19 and srd5beta affects genes related to thyroid and reproductive systems.

This article reviews methods such as stem cell implantation to enhance hair transplant donor supply but reports no new clinical findings.

This study found that PBX1 enhances the proliferation and reprogramming of hair follicle mesenchymal stem cells by activating the AKT/GSK3β signaling pathway, promoting NANOG expression, and inhibiting apoptosis.