July 2024 in “Journal Archives of Health” Woolly hair is a rare genetic condition with no effective treatments.
August 2022 in “Indonesian Journal of Medical Chemistry and Bioinformatics” Certain herbal compounds might help prevent hair loss in menopausal women by activating Vitamin D receptors.
September 2016 in “Journal of Dermatological Science” Certain gene mutations in Japanese people are linked to different types of hair loss, with some causing mild hair thinning and others leading to complete baldness.
June 2010 in “Melanoma research” LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
January 2016 in “Journal of Clinical Dermatology” Trichoscopy helps diagnose and assess the severity of two types of hair loss diseases, androgenetic alopecia and alopecia areata.
243 citations,
September 2016 in “Dermatology and Therapy” Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.
127 citations,
July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
74 citations,
January 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the DSG4 gene can cause a rare hair disorder similar to monilethrix.
42 citations,
October 2012 in “Dermatologic Clinics” Trichoscopy is a useful tool for diagnosing different hair and scalp diseases without surgery.
36 citations,
February 2007 in “Journal of biological chemistry/The Journal of biological chemistry” The vitamin D receptor can work without its usual activating molecule.
30 citations,
March 2015 in “Journal of Dermatology” Hair thickness differences help diagnose hair loss severity.
24 citations,
April 2012 in “Developmental Biology” Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
23 citations,
November 2018 in “Development, Growth & Differentiation” Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
22 citations,
April 2017 in “Cell Stem Cell” Skin wounds can create fat cells that help regenerate hair follicles, with BMP signaling playing a crucial role in this process.
22 citations,
September 2014 in “JAMA dermatology” Ichthyosis with confetti is a genetic skin disorder with consistent ectodermal malformations and various KRT10 gene mutations.
19 citations,
November 1993 in “Mammalian Genome” A gene mutation in mice causes permanent hair loss and skin issues.
15 citations,
April 2017 in “Cell Stem Cell” Some brain cancer cells avoid immune system detection, and certain treatments could target this to slow their growth; also, certain fat cell precursors help regenerate hair and skin after injury.
12 citations,
January 2019 in “International Journal of Trichology” Trichoscopy is useful for detecting and monitoring androgenetic alopecia.
9 citations,
May 2002 in “PubMed” Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.
6 citations,
May 1997 in “Journal of Dermatological Science” Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.
4 citations,
January 2012 in “Springer eBooks” The document concludes that signs of male and female pattern baldness include uneven hair thickness, yellow spots, skin discoloration around hair follicles, more thin and soft hairs, and many hair follicles with just one hair.
3 citations,
January 2021 in “Medicinski arhiv” Trichoscopy, a hair loss evaluation technique, found that people with Androgenetic Alopecia have more thin hairs, yellow dots, and perifollicular discoloration than healthy individuals.
3 citations,
October 2011 in “JAT. Journal of applied toxicology/Journal of applied toxicology” Doxazosin mesylate and saw palmetto cause genetic changes in fruit flies.
1 citations,
January 2021 in “Springer Proceedings in Materials” Researchers developed a new method to clearly see and label hair proteins with minimal errors using advanced freezing and microscopy techniques.
1 citations,
January 2019 in “Advances in stem cells and their niches” Epidermal stem cells are crucial for skin health and problems with them can cause issues like poor wound healing, cancer, and aging.
September 2024 in “Indian Journal of Dermatology” Trichoscopy effectively diagnoses and assesses the severity of androgenetic alopecia.
September 2023 in “Zenodo (CERN European Organization for Nuclear Research)” Trichoscopy helps diagnose and track treatment for hair loss in men and women.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The study developed a 3D model that closely imitates remaining ovarian cancer after treatment and identified a potential drug targeting resistant cancer cells.
July 2022 in “المجلة العراقية للصيدلة” Most women with excessive hair growth (hirsutism) also experience a common type of non-scarring hair loss called Androgenetic alopecia with telogen effluvium.
March 2021 in “CRC Press eBooks” The document concludes that different patterns of hair thickness and scalp changes can help diagnose types of non-scarring hair loss.