17 citations
,
December 2008 in “Dermatology” This study found that adding metformin to IPL therapy in women with PCOS significantly improved insulin sensitivity and reduced hirsutism compared to IPL therapy alone.
16 citations
,
December 2018 in “Skin pharmacology and physiology” This study found that in people with alopecia areata, oxidative stress indicators were higher and specific enzyme activities were lower compared to healthy controls, suggesting oxidative stress's significant role in disease pathogenesis.
15 citations
,
March 2020 in “Journal of cosmetic dermatology” This review examines non-surgical methods for rejuvenating the periorbital area and highlights the growing role of platelet-rich plasma, but it reports no new clinical findings.
15 citations
,
January 2009 in “International Journal of Andrology” This study found that an alcoholic extract of Glycyrrhiza glabra significantly reduced prostate weight and serum testosterone in castrated rats given testosterone, indicating potential antiandrogenic properties.
13 citations
,
February 2022 in “JAMA Dermatology” This meta-analysis found that spironolactone use was linked to a decreased risk of prostate cancer but not to a significant risk increase for several other cancers, although the evidence certainty was low.
12 citations
,
January 2018 in “Journal of Drug Delivery Science and Technology” This study developed solid lipid nanoparticles for effective delivery of shRNA-encoding plasmids, showing reduced 5α-reductase levels in DU-145 cells without significant cytotoxicity.
12 citations
,
June 2009 in “Journal of Cosmetic Dermatology” This study reports the first cases of loose anagen hair syndrome in dark-skinned children from Upper Egypt, noting it may be under-diagnosed and primarily causes cosmetic concerns without affecting general health.
11 citations
,
February 2025 in “Journal of Science Advanced Materials and Devices” This study reported that nanofibrous scaffolds made from a PVA and flaxseed extract combination showed enhanced antimicrobial activity and significantly better wound healing in vitro compared to pure PVA fibers.
11 citations
,
December 2017 in “Orphanet Journal of Rare Diseases” This study found a previously unreported ST14 gene mutation in a patient with ichthyosis-hypotrichosis syndrome, highlighting novel skin and hair characteristics and emphasizing the critical role of the Asp482 amino acid in matriptase activation.
11 citations
,
September 2016 in “Journal of virological methods” In this study, rabies virus antigens were detected in the outer root sheath of the follicle-sinus complex in the muzzle skin of rabid dogs, suggesting its usefulness as an alternative diagnostic specimen.
11 citations
,
August 2010 in “Journal of Dermatology” This case report describes occipital hair transplantation for therapy-resistant alopecia areata in eyebrows, observing 80% hair re-growth two years post-surgery and suggesting surgical options may be useful for stable cases.
10 citations
,
August 2024 in “ACS Omega” This review discusses the use of nanomaterials in cosmetics, highlighting their benefits like enhanced stability and skin penetration, while also noting potential health risks and the role of natural ingredients in formulations.
10 citations
,
February 2021 in “Pharmaceutics” In this study, the novel fatty acid-conjugated tetrapeptide Palmitoyl-GDPH enhanced wound healing in rats by improving re-epithelialization and collagen deposition with minimal toxicity observed at the used dosage.
10 citations
,
August 2020 in “Current protocols in stem cell biology” This paper presents a protocol for differentiating human-induced pluripotent stem cells into keratinocyte progenitor cells and keratinocytes, suggesting potential applications for hair follicle restoration and burn or ulcer therapy.
10 citations
,
March 2018 in “Anais Brasileiros De Dermatologia” This study observed that androgenetic alopecia had a more significant negative impact on psychological parameters in females than males, with some differences in psychosexual outcomes based on clinical stages.
9 citations
,
October 2024 in “Food Science and Biotechnology”
9 citations
,
June 2019 in “Archives of Dermatological Research” This study found that both topical calcipotriol and narrow band ultraviolet B phototherapy improved hair regrowth and vitamin D3 levels in alopecia areata patients.
9 citations
,
January 2013 in “Case reports in emergency medicine” This case study reports that Citrullus colocynthis can cause severe gastrointestinal symptoms, including rectorrhagia and mucosal erosion, highlighting the need for awareness of its potential side effects.
9 citations
,
November 2012 in “Archives of Dermatological Research” MC4R gene variants not linked to female hair loss.
7 citations
,
October 2022 in “Expert opinion on emerging drugs” This review reports on new and effective drug developments for treating severe alopecia areata, including oral baricitinib, but emphasizes that no treatment guarantees permanent remission or works for all patients, with high recurrence rates after stopping medication.
7 citations
,
March 2020 in “Lasers in Medical Science” LLLT is a safe, promising hair loss treatment, but more research needed.
7 citations
,
July 2019 in “Advances in preventive medicine” Among 255 subjects with diabetes, this study found an 88.4% prevalence of skin conditions and 15.7% prevalence of nail manifestations, linked with factors like age and disease duration.
7 citations
,
September 2007 This study found that valproate sustained-release monotherapy provided effective short-term seizure control and was well tolerated in newly-diagnosed epileptic patients with partial seizures in the Gulf Cooperation Council countries.
6 citations
,
June 2024 in “Biofabrication” This study used digital-light-processing bioprinting to create a 3D skin-on-a-chip model with a miniaturized vascular network to closely study immune cell interactions similar to real human skin, demonstrating the potential to analyze immune-T cell trafficking influenced by skin signals.
6 citations
,
January 2015 in “International Journal of Pediatrics and Adolescent Medicine” This report describes two cases of hair tourniquet syndrome successfully treated with hair removal cream, noting its effectiveness as a less invasive option compared to traditional methods like incisions or blunt probe cutting.
6 citations
,
April 2006 in “Lupus” This study reports that hair in women with systemic lupus erythematosus is thinner than in healthy women, but not significantly different from women with rheumatoid arthritis.
6 citations
,
December 2002 in “International journal of cosmetic surgery and aesthetic dermatology” This article discusses the delta lift procedure, which reportedly achieves a more youthful look with fewer complications than conventional face lifts by using limited skin excision and tightening techniques.
5 citations
,
June 2024 in “Archives of Dermatological Research” This study found that fractional Er:YAG laser combined with platelet-rich plasma resulted in greater skin repigmentation in patients with localized stable vitiligo compared to microneedling with platelet-rich plasma, with fewer side effects reported in the laser group.
5 citations
,
January 2024 in “BMC Cancer” In this descriptive study, researchers assessed the most common short-term side effects of anthracycline and taxane-based chemotherapy in 122 Moroccan women with localized breast cancer, documenting frequent systemic, gastrointestinal, dermatological, neurological, musculoskeletal, and ocular toxicities.
5 citations
,
January 2021 in “Journal of Saudi Chemical Society” This study analyzed watercress oil and confirmed its phytochemical profile, UV absorption properties, and potential efficacy for hair growth, supporting traditional hot oil applications.