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    Glossary Hair Medulla

    innermost layer of a hair strand, often containing air spaces

    The hair medulla is the innermost layer of a hair strand, often composed of soft, spongy cells that may contain air spaces. While its exact function is not fully understood, it is thought to contribute to the hair's overall strength and may play a role in the hair's ability to insulate. Not all hair types have a medulla, and its presence can vary between individuals and even among different hairs on the same person.

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    1. [Contribution to hair medulla study (author's transl)]. PubMed · 1981 · 4 citations
    2. Characterization of Hair Follicles in Hirosaki Hairless Rats with Deletion of Basic Hair Keratin Genes. Enlarged Medulla, Loss of Cuticle and Long Catagen Hirosaki University Repository for Academic Resources (Hirosaki University) · 2009 · 3 citations
    3. A New Approach to Obtain Attractive Hair: Hair Medulla Care Journal of Society of Cosmetic Chemists of Japan · 2023 · 2 citations
    4. Hair Medulla and its variations in Doshaja Prakruti – An observational study International Journal of Ayurvedic Medicine · 2025
    5. Faculty Opinions recommendation of The keratins of the human beard hair medulla: the riddle in the middle. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2010
    6. CASE REPORT: SCABIES WITH NORMOCYTIC NORMOCHROMIC ANEMIA AND ABNORMALITIES IN THE HAIR MEDULLA IN DOMESTIC CATS VITEK Bidang Kedokteran Hewan · 2024
    7. ABO Blood Grouping of Non-medullated Scalp Hair Using Immunohistochemical Staining Nihon Hou Kagaku Gijutsu Gakkaishi · 2010
    8. Type II Epithelial Keratin 6hf (K6hf) Is Expressed in the Companion Layer, Matrix, and Medulla in Anagen-Stage Hair Follicles Journal of Investigative Dermatology · 2003 · 60 citations
    9. Panax ginseng prevents apoptosis in hair follicles and accelerates recovery of hair medullary cells in irradiated mice. PubMed · 1998 · 22 citations
    10. ABSENCE OF H2O2 BREAKDOWN IN HUMAN HAIR MEDULLA IMPLICATIONS IN FOLLICULAR MELANOGENESIS International journal of research - granthaalayah · 2018 · 1 citations
    11. Relative studies between hair index, hair area, and medullary index with age and sex in Thai scalp hair Forensic science international · 2016 · 9 citations
    12. Medulla loss of scalp hair in breast cancer patients determined by near-infrared microscopy Journal of Biomedical Optics · 2019 · 4 citations
    13. New Aspects of the Structure of Human Scalp Hair-II: Tubular Structure and Material Flow Property of the Medulla. PubMed · 2019 · 1 citations
    14. The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle 2009 · 87 citations
    15. Keratins of the human occipital hair medulla: androgenic regulation of<i>in vitro</i>hair keratin K37 expression British Journal of Dermatology · 2013 · 6 citations
    16. HAIR-LOSS AS DEFICIENCY TEST OF MEDULLECTOMY IN RATS Journal of Endocrinology · 1940 · 96 citations
    17. Nanoindentation of Hair Cortex and Medulla Regions 2019 · 3 citations
    18. Analysis of Lipids in the Medulla of Japanese Hair and Their Function Cosmetics · 2018 · 7 citations
    19. Ultrastructural immunolocalization of involucrin in the medulla and inner root sheath of the human hair Annals of anatomy · 2011 · 7 citations
    20. Corrections to: "The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle" Journal of Investigative Dermatology · 2010
    21. Characterization of hair follicles in Hirosaki hairless rats with deletion of basic hair keratin genes : enlarged medulla, loss of cuticle and long catagen Medical Entomology and Zoology · 2008
    22. The occurrence of the ε-(γ-glutamyl)lysine cross-link in the medulla of hair and quill Biochimica et Biophysica Acta (BBA) - Protein Structure · 1972 · 49 citations
    23. Novel Type I Hair Keratins K39 and K40 Are the Last to be Expressed in Differentiation of the Hair: Completion of the Human Hair Keratin Catalog Journal of Investigative Dermatology · 2007 · 70 citations
    24. A discourse on human hair fibers and reflections on the conservation of drug molecules International Journal of Legal Medicine · 1996 · 47 citations
    25. Measuring changes in chemistry, composition, and molecular structure within hair fibers by infrared and Raman spectroscopic imaging Journal of Biomedical Optics · 2011 · 42 citations
    26. The cDNA-deduced amino acid sequence for trichohyalin, a differentiation marker in the hair follicle, contains a 23 amino acid repeat. 1990 · 39 citations
    27. Morphology and ultrastructure of antler velvet hair and body hair from red deer (<i>Cervus elaphus</i>) Journal of morphology · 2010 · 18 citations
    28. Lipid loses and barrier function modifications of the brown‐to‐white hair transition Skin research and technology · 2019 · 12 citations
    29. Spectral histology of hair and hair follicle using infrared microspectroscopy International Journal of Cosmetic Science · 2024 · 1 citations
    30. Seasonal Gene Expression Profile Responsible for Hair Follicle Development in Angora Goats 2023