6 citations,
November 2023 in “Clinical Pharmacokinetics” Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.
6 citations,
August 2017 in “Physiological Research” Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.
4 citations,
June 2013 in “The Journal of Rheumatology” The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.
3 citations,
February 2021 in “Molecules” A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
2 citations,
September 2023 in “Aging” Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.
2 citations,
January 2019 in “Medizinische Genetik” The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
1 citations,
September 2023 in “Dermatology and therapy” More research is needed to find the best treatment for dissecting cellulitis of the scalp.
1 citations,
June 2012 in “Springer eBooks” Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.
April 2024 in “Research Square (Research Square)” MSC-protein helps regenerate gum tissue and bone.
September 2023 in “Fides et Ratio” The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.
September 2023 in “Biology of reproduction” New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
February 2019 in “Journal of the Faculty of Agriculture Kyushu University” Terpene concentrations in coniferous trees are highest in spring and summer, making these seasons best for extracting essential oils.
January 2019 in “Springer Reference Medizin” Follicle Stimulating Hormone is important for fertility.
December 2013 in “Biomedical and biopharmaceutical research” Nanotechnology shows promise for better drug delivery and cancer treatment.
January 2012 in “Springer eBooks” Lupus can cause different skin problems, and treatments like quitting smoking and using certain creams or medicines can help.
The document listed various medical job opportunities with competitive benefits and living conditions.
1 citations,
March 2022 in “Dermatology Research and Practice” Higher CD70 and CD27 gene expression in alopecia areata lesions predicts disease severity and activity.
62 citations,
January 2009 in “Biochemistry” Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
47 citations,
June 2017 in “The FEBS journal” Disabling the FGF5 gene in sheep leads to longer wool.
12 citations,
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Laminin 332 is essential for normal skin cell behavior and structure.
43 citations,
May 1999 in “Journal of Biological Chemistry” Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.
38 citations,
December 2020 in “International journal of biochemistry & cell biology” Keratin proteins are essential for keeping the cells in the human colon healthy and stable.
34 citations,
June 2015 in “Journal of cardiovascular pharmacology and therapeutics” Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.
November 2023 in “ACS Omega” New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
36 citations,
August 2022 in “Molecular Therapy — Nucleic Acids” Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
22 citations,
April 2012 in “The American journal of pathology” Loss of Msx2 function causes eye development issues similar to Peters anomaly.
18 citations,
November 2012 in “Current opinion in urology” Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.
7 citations,
September 2022 in “Communications biology” Omega-6 fats in certain cells boost male hormone production.
5 citations,
September 2023 in “Nutrients” Soy protein with isoflavones reduces wrinkles and improves skin hydration in postmenopausal women.