research Skin Biology: Understanding Biological Targets for Improving Appearance
The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.
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research Efficient Genome Editing Using CRISPR/Cas9 Ribonucleoprotein Approach in iPS Cells for Recessive Dystrophic Epidermolysis Bullosa
Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.
research Cornification
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
research Skin Regeneration: Strategies and Innovations
New materials and methods could improve skin healing and reduce scarring.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research Ultrastructural Evaluation of the Radioprotective Effects of Melatonin Against X-Ray-Induced Skin Damage in Albino Rats
Melatonin may reduce skin damage caused by X-rays in rats.
research Clinical and Microscopic Features of Generalized Discoid Lupus Erythematosus in Dogs (10 Cases)
Dogs with generalized discoid lupus erythematosus have similar symptoms to humans and need continuous treatment.
research Stem Cell and Extracellular Matrix-Related Molecules Increase Following Melatonin Treatment in the Skin of Postmenopausal Rats
Melatonin treatment helps improve skin health in postmenopausal rats.
research Bioengineering Skin Constructs
Future research should focus on making bioengineered skin that completely restores all skin functions.
research Effect of Ginsenoside Rd on Dermal-Epidermal Junction in Fibroblast
Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.
research Age-Dependent Loss of the Stemness and Antimicrobial Defense Function of Dermal Fibroblasts Is Mediated by TGFbeta
Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
research The Effects of 3-Hydroxy of Kaempferol on Interfollicular Epidermal Stem Cell Fate
Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.
research Skin, Genetic Defects, and Aging
Genetic defects and UV radiation cause skin damage and aging.
research Skin Wound Healing in Humans and Mice: Challenges in Translational Research
The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
research Epithelial-To-Mesenchymal Transition in Cutaneous Wound Healing: Where We Are and Where We Are Heading
The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.
research Extracellular Matrix Degradation Products and Low-Oxygen Conditions Enhance the Regenerative Potential of Perivascular Stem Cells
Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.
research Induction of Dark Keratinocytes by 12-O-Tetradecanoyl-Phorbol-13-Acetate and Mezerein as an Indicator of Tumor-Promoting Efficiency
TPA is about 50 times more effective at promoting tumors than MZ.
research A Practical Guide for the Study of Human and Murine Sebaceous Glands In Situ
The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.
research The HoVert Technique: A Novel Method for the Sectioning of Alopecia Biopsies
The HoVert technique is a simple, cost-effective new method that improves alopecia diagnosis by allowing detailed analysis from a single biopsy.
research Vertical vs. Transverse Sections in Alopecia Biopsy Diagnosis
Both vertical and transverse sections are useful for diagnosing alopecia, but using both methods together is best.
research Development, Structure, and Keratin Expression in C57BL/6J Mouse Eccrine Glands
The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.
research Friends Turned Foes: Angiogenic Growth Factors Beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Reduced Cell Cohesiveness of Outgrowths from Eccrine Sweat Glands Delays Wound Closure in Elderly Skin
Older people's sweat glands are less effective at helping skin wounds heal due to weaker cell connections.
research Molecular Pathology of Skin Adnexal Tumors
New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
research Transforming Growth Factor-β, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes
Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.
research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
The PP2A-B55α protein is essential for brain and skin development in embryos.
research Dermatopathology and Molecular Genetics
Combining skin tissue pathology with genetics has greatly improved the diagnosis and understanding of certain skin diseases.
research Concurrent Follicular Dysplasia and Interface Dermatitis in Boxer Dogs
Boxer dogs may have a genetic skin condition that worsens seasonally and can be treated with certain medications.
research Thy1 Marks a Distinct Population of Slow-Cycling Stem Cells in the Mouse Epidermis
A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.
research Post-Traumatic Erosive Dermatosis of the Scalp: A Hypergranulated Variant
Elderly men with a scalp condition healed in about 26 days using specific creams and dressings, with no return of the condition in 6 months.