578 citations
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April 1993 in “Cell” This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.
29 citations
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January 2003 in “Genomics” A new mouse mutation causes skin and hair issues, influenced by another gene.
This study mapped the curly mutation in mice to a specific region on chromosome 11, identifying it as a candidate model for studying human genetic hair disorders.
January 2024 in “Indian Journal of Pharmaceutical Sciences” This study hypothesizes that curly hair is shaped by the contraction of the Arrector Pili Muscle within the follicle, potentially modifiable through muscle-relaxing treatments, but further research is needed to confirm this mechanism.
1 citations
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March 2023 in “Frontiers in Cardiovascular Medicine” A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.
December 2023 in “Data in Brief” In this study, the researchers conducted tensile tests on individual curly human hair fibers sourced from a female donor and found distinct mechanical properties under various conditions, including different strain rates and temperatures, both dry and in saline immersion.
January 2007 in “Proceedings of the Korean Fiber Society Conference” New resin B makes artificial hair fibers hold curls longer than traditional resin A.
1 citations
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March 2023 in “Journal of Natural Fibers” This study explored using tyrosine as a cross-linking agent for curling Asian hair and found that it could shape hair effectively before washing without damaging the fibers, though the method was less effective after washing compared to commercial products.
September 2025 in “Cosmetics” In this study, researchers found that the lipid composition in hair significantly affects water diffusion and may explain differences in dyeing and cosmetic treatment responses between Asian and European hair, with CP2 fibers having more lipids than CP3 fibers.
This paper explores the diverse patterns and social significance of Black hair, approaching it as an art form, mathematical pattern, and ethnomathematic entity, and seeks to dispel myths while highlighting its vast possibilities.
June 2023 in “Frontiers in Genetics” This study suggests that the curly hair phenotype in Mangalitza pigs may involve complex gene interactions related to calcium signaling and lipid metabolism, rather than changes in TRPM2 or CYP4F3 expression.
April 2024 in “Journal of Pakistan Association of Dermatologists” In this study of male patients with non-curly hair, the researchers observed a significant occurrence of folliculitis nuchae linked to close haircuts and shaving, with treatment effectiveness varying by disease phase and best results seen in early stages.
July 2024 in “JAAD Case Reports” This study reported three cases where patients experienced changes in hair curl patterns after acute lupus alopecia and alopecia areata, with baseline hair texture restored following medical treatment.
65 citations
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March 2017 in “Experimental Dermatology” This review discusses the genetic and biological factors influencing hair curliness, revealing strong links to specific protein variations, and reports no new clinical results.
July 2025 in “Case Reports in Dermatology” This case report highlights that early signs like pili torti may precede lichen planopilaris in some patients, emphasizing the importance of timely intervention to prevent permanent hair loss.
2 citations
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July 2013 in “Acervo Digital da Universidade Estadual Paulista (Universidade Estadual Paulista)” This study found that the shampoo formulation with Polyurethane-14 and AMP-acrylates copolymer improved curl definition and reduced frizz and volume in natural and curly hair tresses compared to the control.
July 2026 in “Open Minds International Journal” This review suggests that multifunctional cosmetic systems, particularly HIVEN Curl Code ®, may help control frizz and maintain curl definition in highly curly hair by utilizing various conditioning and biofunctional ingredients.
5 citations
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November 2012 in “Journal of the American Academy of Dermatology” This case report describes a 3-year-old girl with short hair since birth, showing normal hair density with many vellus and intermediate hairs, and no hair shaft abnormalities.
October 2018 in “Journal of Advances in Medical and Pharmaceutical Sciences” This study observed that platelet-rich plasma treatment significantly reduced hair loss and improved hair density in female Libyan patients with curly hair suffering from androgenic alopecia.
This paper offers detailed tables of genotypic and phenotypic data on horses, including markers, variants, and haplotypes, but reports no new research results.
85 citations
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October 2007 in “International Journal of Dermatology” In this study, researchers found that the curliness of human hair is associated with an asymmetric structure at the cellular level, particularly in the differentiation of the precortex.
26 citations
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October 1999 in “Archives of Dermatology” This discussion suggests that acquired progressive kinking of hair in androgen-dependent scalp areas may indicate the early stages of androgenetic alopecia with a poor prognosis, but it offers no new clinical findings.
20 citations
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May 1992 in “The Journal of Dermatologic Surgery and Oncology” This article discusses patient selection and procedural design for hair transplant surgery without reporting new clinical results; it also considers how hair transplant designs can align with various hairstyles.
18 citations
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January 2015 in “Journal of medical genetics” This review discusses the genetic basis of woolly hair syndrome and its potential link to heart disorders, highlighting recent discoveries of new molecular pathways and suggesting possible future treatment options.
13 citations
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October 2008 in “PubMed” This study examined hair curvature in Japanese women, finding that 47% have curved hair, and identified structural differences in hair fiber, which resemble those in wool fibers.
13 citations
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January 2007 in “Epilepsia” This case report describes a 47-year-old woman who experienced reversible curling of her hair during treatment with valproic acid, suggesting potential side effects on hair texture.
8 citations
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November 2022 in “International Journal of Cosmetic Science” This review discusses the limitations of current hair classification systems and highlights the need for standardized reporting of key hair characteristics to improve study comparisons; it reports no new results.
7 citations
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November 2021 in “Clinical, Cosmetic and Investigational Dermatology” This study describes a novel FUE device that may perform successfully across various patient scenarios, adapting to differences in skin firmness, thickness, and hair curliness.
6 citations
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December 2011 in “Clinical and Experimental Dermatology” A woman developed rare, unexplained curly hair on her scalp and eyelashes.
1 citations
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August 2025 in “Journal of Investigative Dermatology” Genetic studies on hair traits can improve understanding of health and disease.