June 2026 in “Comprehensive Psychoneuroendocrinology” In this study, researchers observed a curvilinear relationship between loneliness and hair cortisol concentration among older adults at elevated cardiovascular risk, with cortisol levels higher at low-to-moderate loneliness and lower at higher loneliness, though results were sensitive to some data exclusions.
March 2026 in “Journal of Pain” Preoperative stress markers alone don't predict chronic post-surgical pain.
February 2026 in “Psychoneuroendocrinology” Lower family income is linked to more stress in parents and more behavior problems in children.
January 2026 in “Open Science Framework” This study examines various methodological factors affecting hair cortisol concentration analysis, finding inconsistent results on the impact of factors like resuspension solution, hair weight, extraction duration, and hair-cutting method.
1 citations
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November 2022 in “Nutrients” This study found that piglets' rapid growth during nursery and lactation was linked to changes in microbiota composition and increased cortisol conversion, highlighting critical early life factors influencing adult microbiota establishment.
August 2015 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia/Arquivo brasileiro de medicina veterinária e zootecnia” This study found that maternal caffeine intake during gestation and lactation can lead to skin lesions like hypotrichosis and alopecia in both mother and offspring rats, irrespective of maternal cortisol levels.
3 citations
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December 2017 in “Journal of Psychiatric Research” This study found that hair cortisol did not indicate expected hypercortisolism in acutely underweight anorexia nervosa patients and did not change significantly during short-term weight restoration.
May 2026 in “Indian Journal of Medical Biochemistry” This review highlights that hair cortisol levels, linked to pregnancy changes and higher in conditions like PCOS, are promising stress biomarkers in female reproductive health, though further research is needed.
September 2025 in “Cosmoderma” This study highlights how the COVID-19 pandemic has exacerbated stress-related dermatological issues like acne and hair loss by affecting skin and hair cycles through stress hormones, emphasizing the need for comprehensive psychoneuroendocrine-informed approaches to diagnosis and treatment.
6 citations
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September 2010 in “Animal” This study found that selecting Angus cattle for early puberty reduced their prolactin levels, which may indicate a response to changing day length.
This study suggests that individuals with severe sickle cell disease, indicated by higher hemoglobin S and ferritin levels, may have lower cortisol levels as shown by reduced hair cortisol content.
33 citations
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January 2017 in “Psychoneuroendocrinology” This study of Danish women found no evidence linking hair cortisol concentration to hair dyeing status or the frequency of hair washing.
296 citations
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October 2018 in “General and Comparative Endocrinology” This review discusses the use of hair cortisol concentration as a marker for chronic stress and long-term cortisol secretion in animals, highlighting its benefits and the need for standardized sampling protocols.
23 citations
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October 2008 in “Experimental and Clinical Endocrinology & Diabetes” This study found that measuring cortisol in human hair can reflect increased cortisol production for up to six months, with the highest concentration in hair closest to the scalp.
2 citations
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January 2009 This study found that the hair cortisol measurement procedure was reliable, unaffected by the choice of tubes, and that hair cortisol concentration correlated moderately with the number of intense aggressions experienced.
October 2022 in “European heart journal” In this study, stress levels measured through hair cortisol concentration gradually increased in the days before an acute myocardial infarction, peaking 15 days before the episode in male patients.
January 2017 in “Qucosa (Saxon State and University Library Dresden)” This study found that plasma protein binding significantly contributes to the shifts in glucocorticosteroid concentration ratios among blood, saliva, and hair, challenging prior assumptions about enzyme inactivation as the main factor.
January 2026 in “Western Journal of Nursing Research” This study found that collecting hair samples for cortisol analysis is feasible in community-dwelling individuals with longstanding multiple sclerosis, although no significant correlation between hair cortisol levels and perceived chronic stress was observed, highlighting the complexity of stress measurement in this population.
122 citations
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October 2013 in “PEDIATRICS” This study observed that cortisol concentrations in hair, indicating prolonged stress, are correlated between mothers and young children, suggesting potential heritable traits or maternal influence.
76 citations
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October 2011 in “Clinica Chimica Acta” In this study, ultraviolet irradiation and immersion in shampoo and hot water significantly reduced hair cortisol, illustrating a two-stage process of cortisol loss that may impact chronic stress assessment.
16 citations
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March 2013 in “Clinica Chimica Acta” Cortisol and cortisone release from hair increases in steps over time during incubation.
3 citations
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January 2012 This study concluded that human sweat contributes to hair cortisol concentrations, potentially affecting interpretations of chronic stress and OSA-related stress levels, with CPAP reducing psychological but not physiological stress after 3 months.
March 2024 in “American journal of veterinary research” This study found that clippers are the safest and most efficient tool for collecting hair samples from companion dogs, with no impact on cortisol concentration compared to scissors.
24 citations
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October 2018 in “Addiction Biology” This study found that alcohol dependence is associated with altered HPA axis functioning, with AD patients showing higher hair cortisol concentrations and reduced ACTH and cortisol levels, irrespective of childhood maltreatment history.
This study found a weak negative correlation between inhaled corticosteroid dose and hair cortisol levels in children with asthma, suggesting that hair cortisol measurement may reflect adrenal function in these children.
3 citations
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October 2021 in “Clinica Chimica Acta” This study found that higher levels of dihydrotestosterone in the parietal region of the scalp may correlate with the clinical presentation of androgenetic alopecia.
January 2018 in “Digital Scholarship - UNLV (University of Nevada Reno)” This study found significantly higher hair cortisol concentrations in black children compared to white children aged 1-4 years, suggesting racial differences in cumulative stress as measured by hair cortisol.
April 2026 in “European Journal of Cardiovascular Nursing” In this exploratory cross-sectional study, the researchers found a strong positive correlation between hair cortisol concentration and physical activity in patients with diastolic heart failure, but no correlation for other heart failure subgroups; perceived stress showed minimal association with physical activity across all subgroups.
November 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” In this study, researchers examined the genetic factors impacting cortisol and DHEA concentrations in the hair of healthy pigs; they found that cortisol levels were heritable and genetically correlated with behavioral stress responses, suggesting these hormones could potentially serve as indicators for selecting disease-resilient pigs.
January 2018 in “Springer eBooks” Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.