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Studying rare genetic disorders can help us understand and treat common diseases better.

The editorial stresses the importance of COVID-19 vaccination and ongoing contributions to the journal.

PCOS is a common condition in women that can lead to infertility and other health issues, and it's diagnosed by specific criteria with various treatment options available.

Exposure to plastics may increase the risk of irregular menstrual cycles and symptoms of hormone imbalance in teenage girls.

STIM1 is essential for sweat secretion.

Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.

Pramipexole can cause side effects like dizziness, sleepiness, hallucinations, and low blood pressure, and it's important to educate patients and keep doses low.

Critical illness can lead to long-lasting physical and psychological problems, requiring ongoing, specialized care and rehabilitation.

Men with male pattern baldness have increased arterial stiffness.

Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.

The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.

Androgenetic alopecia is common, affects self-image, and has no complete cure yet.

Tyrosine kinase inhibitors effectively treat cancers but often cause skin and other side effects.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

Spermidine helps protect against aging by preserving telomere length.

DCP therapy causes side effects like weakness, flushing, headaches, and taste changes, but less frequently causes hypertension and diabetes.

A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.

L-Lysine may help with various health conditions, but results are inconsistent for herpes treatment and its potential in other therapies is still being explored.

The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.

Transnasal cooling could reveal new insights into various physiological conditions and may be a natural way to transfer heat from the brain.

Psoriasis is a common, genetically influenced skin disease worsened by stress and lifestyle, but targeted treatments are promising.

Procyanidins may have antioxidant, heart health, cancer-fighting, anti-inflammatory, anti-diabetic, liver-protective, and other health benefits with high efficiency and low toxicity.

Metabolic syndrome can cause serious health issues and should be considered when treating women with severe acne.

Cepharanthine helps reduce cell aging caused by the cancer drug Doxorubicin by boosting cell cleanup processes.

A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.

Untreated Sheehan's Syndrome caused severe heart failure in a woman, which improved with hormone and heart failure treatment.

Skin symptoms like fragile skin and easy bruising can indicate Cushing's syndrome, which requires early diagnosis and treatment to prevent serious health issues.