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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

The virus was not found in the semen and urine of a man who tested positive for COVID-19.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Finasteride effectively treats frontal hair loss with few side effects.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Androgens can help prevent memory problems caused by apoE4.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.