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Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Stem cell niches support, regulate, and coordinate stem cell functions.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.