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The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.