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The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.

Fat cells are important for tissue repair and stem cell support in various body parts.

Mutations in the KRT85 gene cause hair and nail problems.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Pseudopelade of Brocq is a unique hair loss condition, but its cause and development are still not fully understood.

Dutasteride more effectively treats hair loss than finasteride, but may increase risk of altered libido.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

ROXY proteins help plants respond to nitrate shortage by affecting nutrient sensing and growth.

A male with aromatase deficiency improved bone health with estradiol treatment.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

Feed restriction in sheep leads to finer wool fibers but may reduce wool quality.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Aromatase inhibitor therapy for breast cancer increases the risk of hair loss and thinning.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.