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510-540 / 1000+ resultsresearch Preparation of finasteride capsule and its stability
This study developed a new finasteride capsule with accurate dosage and good stability, showing potential as an effective oral preparation with a tentative two-year shelf life.
research Google allows advertisers to target the sensitive informational queries of cancer patients
This study reports that alternative cancer clinics spent over $15 million on Google ads in the past decade, directing 44.4% of their website traffic from these ads, which targeted sensitive search queries of cancer patients seeking alternative treatments.
research Qualitative study for finasteride detection in the prostate delivered by reversible inhibition of sperm under guidance – Prostate hair (RISUG-PH™) vas injectable implant
This study confirmed that an injectable implant known as RISUG-PH™, when administered via the vas deferens, successfully delivers the drug Finasteride to the prostate in male rats for up to 28 days, suggesting a potential localized alternative to oral delivery methods.
research Enriched-GF: A Reproducible High-Yield Autologous Blood-Derived Growth Factor Method for Regenerative Medicine
In this study, researchers developed a new method called Enriched-GF, which enhances growth factor recovery from platelet concentrates through a combination of glass bead activation, freeze-thaw cycling, and calcium stimulation, outperforming conventional methods by providing higher and more consistent yields for regenerative medicine applications.
research 547 CDK9 Kinase Activation in Association with AFF1-SEC Initiate Epidermal Progenitor differentiation
This study reported that an HS-associated NCSTN mutation in iPSC-derived skin organoids led to altered hair follicle stem cell differentiation and increased expression of proteins linked to HS inflammation.
research Industry Updates from the Field of Stem Cell Research and Regenerative Medicine in December 2019
This article provides industry updates on stem cell research and regenerative medicine from December 2019 and reports no new research findings.
research 2‐Deoxy‐d‐glucose enhances tonic inhibition through the neurosteroid‐mediated activation of extrasynaptic GABAA receptors
This study demonstrated that the glycolytic inhibitor 2-deoxy-D-glucose enhances antiseizure effects by potentiating extrasynaptic tonic GABAergic inhibition through neurosteroidogenesis in hippocampal slices.
research Efficient delivery of transgenes to human hair follicle progenitor cells using topical lipoplex
research Fabrication of Bio-Based Gelatin Sponge for Potential Use as A Functional Acellular Skin Substitute
This study found that crosslinking buffalo gelatin with different methods can modify its properties and potential as a skin substitute, though double-crosslinking may increase immunogenicity slightly.
research Study of the composition of 140 shampoos: similarities and differences depending on the sales channel used
This study concluded that shampoos sold in pharmacies generally contain fewer regulated allergens under EU law compared to those sold in mass-market stores or by mail order, and pharmacy-sold baby shampoos were allergen-free.
research Adipocyte-Derived Amino Acid Storage Proteins are Required for Germline Stem Cell Maintenance in Adult Drosophila Females
This study discovered that in *Drosophila*, knockdown of specific storage proteins in adipocytes decreased germline stem cell maintenance, implicating a role for these proteins in adult tissue regulation.
research Glossary
This abstract provides definitions and descriptions of various medical and scientific terms but reports no new research findings.
research BIOBOARD
This collection of research news highlights various scientific advancements, including discoveries in anti-cancer compounds, new cell types that boost immunity, and a potential Parkinson's breakthrough in Australia, among others from China, India, Korea, Singapore, and Thailand.
research 587 Efficacy and Safety of topical KX-826 in Male Subjects with Androgenetic Alopecia:A Multicenter, Randomized, Double-blind, Placebo-controlled Phase II Study
Among men with androgenetic alopecia, this study found that taking 5 mg of KX-826 twice daily significantly increased hair count compared to a placebo, with the treatment being well-tolerated and no serious adverse effects reported.
research Effective combination therapy for telogen hair loss
In this study, 20 patients with telogen alopecia showed reduced hair loss and improved hair quality after 9 weeks of treatment with the topical product "Time to Grow" and the dietary supplement "Thick and Strong Hair.
research Hair Growth Promotion Activity of Bacillus Cereus Strain, An Endophytic Bacterium, Isolated from Eclipta Prostrata (L.) L
research Development of a Carvedilol-Loaded Solid Self-Nanoemulsifying System with Increased Solubility and Bioavailability Using Mesoporous Silica Nanoparticles
This study found that the solid self-nanoemulsifying drug delivery system improved the oral bioavailability of carvedilol significantly compared to the drug alone, enhancing its solubility, dissolution, AUC, and Cmax.
research Determination of illegal adulteration of dietary supplements with synthetic hair-growth compounds by UPLC and LC-Q-TOF/MS Part A Chemistry, analysis, control, exposure & risk assessment
This study developed and validated a method using UPLC-PDA and LC-Q-TOF/MS to identify and measure prohibited substances in dietary supplements, showing reliable detection of compounds like minoxidil and finasteride.
research 653 Substance P ameliorates epidermal thickness, basal cell density, and asymmetric stem cell self-renewal in skin with decreased sensory innervation
Substance P helps restore skin thickness and cell renewal when sensory nerves are reduced.
research Steroid Sulfatase in the Human Hair Follicle Concentrates in the Dermal Papilla
This study found that steroid sulfatase in the dermal papilla of hair follicles metabolizes dehydroepiandrosterone sulfate to support the development of androgenetic alopecia, suggesting potential for steroid sulfatase inhibitors as treatments.
research Hair growth‐promoting effects of Camellia seed cake extract in human dermal papilla cells and C57BL/6 mice
This study found that de-saponinated Camellia seed cake extract promotes hair growth in vitro and in vivo by enhancing dermal papilla cell proliferation and modulating signaling pathways and growth factor expression.
research Compatibility of Cetirizine Hydrochloride, Dutasteride, Hydrocortisone Acetate, Nicotinamide, Progesterone, and Pyridoxine Hydrochloride in TrichoSolTM, A Natural Vehicle for Hair Solutions.
In this study, researchers assessed the physical-chemical and microbiological stability of various pharmaceutical ingredients in the vehicle TrichoSolTM, finding differing beyond-use dates for the compounds, such as 180 days for cetirizine hydrochloride, but only 90 days for progesterone at higher concentrations.
research Advanced Skin Antisepsis: Application of UVA-Cleavable Hydroxyethyl Starch Nanocapsules for Improved Eradication of Hair Follicle-Associated Microorganisms
This study suggests that UVA-responsive nanocapsules may provide an effective method for skin antisepsis by releasing ethanol and reducing microorganisms within hair follicles on ex vivo porcine ear skin.
research Rapid in situ formation of a double cross-linked network hydrogels for wound healing promotion
This study developed a hydrogel dressing incorporating angelica polysaccharides, demonstrating enhanced wound healing properties in a mouse model by promoting rapid hemostasis, tissue healing, and new blood vessel formation compared to Tegaderm™ film.
research Ginseng and ginseng byproducts for skincare and skin health
This review discusses recent in vitro and in vivo research suggesting that components of ginseng, such as ginsenosides and gintonin, may have potential skincare benefits, including anti-aging effects and treatment of skin conditions like atopic dermatitis and hypertrophic scars.
research Culture and characterization of rat hair follicle stem cells
research MP27-18 STATEWIDE GEOGRAPHIC PRICE VARIATION OF GENERIC BPH MEDICATIONS
This study found that big chain pharmacies in Pennsylvania charged significantly higher prices for generic BPH medications compared to independent pharmacies, which had more regional price variation.
research Transforming human hair fibers into carbon dots: Utilization in flexible films, fingerprint detection, counterfeit prevention and Fe3+ detection
Scientists made glow-in-the-dark dots from human hair that can detect iron, prevent counterfeiting, and reveal fingerprints.
research Unmasking Chemokine‐Inducing Specificity in Oligosaccharide Biomaterial to Promote Hair Growth (Adv. Mater. 6/2024)
In this study, researchers discovered that a newly identified oligosaccharide, OG6, promotes hair growth by activating hair follicles, achieved by revealing its hidden activity from a larger molecule structure.