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This review discusses a new multidisciplinary guideline for treating male hypogonadism and emphasizes a comprehensive approach but reports no new experimental results.

This publication reviews the World Professional Association for Transgender Health's Standards of Care for supporting transgender and gender nonconforming people, with adjustments needed for diverse global contexts and no new clinical results.

This study found that the peach gene CTG134, involved in auxin-ethylene interactions, plays a role in hormonal regulation during root hair formation in Arabidopsis and tobacco.

This study found that in male mouse pancreatic islet β cells, testosterone enhances glucose-stimulated insulin secretion by being locally converted into dihydrotestosterone and estradiol.

This review highlights the dermatological needs of transgender and gender diverse individuals in Australia, emphasizing the role of dermatologists in managing skin and hair conditions related to gender affirmation and hormone therapy.

This study found that sacituzumab govitecan improved health-related quality of life in most areas for patients with HR+/HER2− metastatic breast cancer compared to chemotherapy, except for increased diarrhea, supporting its use as a treatment option.

This review discusses the role of athletic trainers in the medical affirmation and care of transgender and gender-diverse individuals, but it reports no new research findings; the authors emphasize the need for interprofessional collaboration.

This study reported that a gemcitabine and pemetrexed regimen was moderately active in advanced NSCLC but did not offer an advantage over the paclitaxel and gemcitabine regimen and is not recommended for further evaluation.

This study emphasizes the necessity of confirming elevated testosterone levels detected by immunoassay with liquid chromatography-tandem mass spectroscopy before pursuing more complex diagnostic evaluations.

This study found that ChatGPT 4.0 and Gemini 1.5 Flash provided more accurate and user-friendly responses to androgenetic alopecia questions than Deepseek R1, suggesting they could be effective tools for patient education with physician guidance.

This review discusses medical interventions that reproductive health experts can provide to transgender and gender diverse youth and reports no new clinical results.

This review discusses the progress and challenges of targeted protein degradation therapies, highlighting the increasing number of degraders in cancer clinical trials and the limited diversity in targeted proteins, primarily focusing on those employing CRL4^CRBN as the E3 ligase.

This study found that while GPT-4 shows high accuracy and efficiency in clinical decision making, physicians' critical thinking and lifelong learning skills remain essential, particularly in addressing and interpreting AI errors in medical settings.

This study found that after a 4-month comprehensive therapy course, 90.5% of patients with androgenetic alopecia and telogen effluvium showed hair condition improvement, highlighting the potential benefits of adjuvant proteoglycan replacement therapy in these conditions.

Targeted testing for telogen effluvium patients can save healthcare costs.

This review summarizes existing clinical guidelines for hormonal therapy in gender dysphoria, observing similarities in international practices and emphasizing the need for more evidence-based research, particularly on GnRH agonists for both trans women and men.

This study found that administering the gut bacterium Thauera sp. strain GDN1 to mice significantly reduced their serum androgen levels, indicating gut bacteria may influence androgen metabolism.

This study found that the Transdermal Delivery System efficiently delivers testosterone systemically and showed bioequivalent hormone concentrations to a known topical gel in healthy males.

In this study, a topical formulation with compounds from the monoterpenoid family significantly improved hair growth indicators like anagen:telogen ratio, hair fall, and visual hair density in men and women with pattern hair loss.

This case report highlights that in postmenopausal women with severe hyperandrogenism, thorough adrenal and pelvic evaluations, hormonal profiling, and permanent pathology are essential for accurate diagnosis and management of androgen-secreting tumors, such as AGCTs, to prevent misdiagnosis and ensure effective treatment.

This article discusses temporal triangular alopecia, emphasizing the need for increased awareness to prevent misdiagnosis and ineffective treatment, but reports no new clinical results.

In this study, PGD2 treatment in keratinocytes increased testosterone production via reactive oxygen species, suggesting a potential role for the NRF2 pathway in androgenic alopecia treatment strategies.

Recombinant human TSG-6 speeds up wound healing in diabetic mice.

In this study, adding TPGS to a minoxidil formulation improved local retention and reduced systemic absorption in certain solvent mixes, particularly with a balance of alcohol and PEG 400.

This study reviewed literature on dermatological changes in transgender and gender diverse individuals during gender affirming medical transition, identifying risks like acne and hypertrophic scars, and provided tailored care recommendations for health professionals.

This case report describes a 3-year-old boy with trichothiodystrophy, highlighting specific MRI findings of diffuse dysmyelination and osteosclerosis that may be unique to the disorder.

This study found that waving virgin human hair with thioglycerol at pH 9.0 using ammonia solution caused less damage than using thioglycolic acid, while maintaining good waving efficiency.

In this study, UVFD and sUVRD techniques revealed distinctive characteristics of GD lesions, suggesting that GD might be more common in younger individuals and females than previously thought, possibly due to underdiagnosis. Incorporating dermatoscopy in exams may help improve GD detection and management.

This research found that the transfer reaction catalyzed by human plasma and guinea pig hair follicle transglutaminases aligns with a ping-pong mechanism involving peptide-bound glutamine.

In this animal study, AGO (agomelatine) effectively alleviated testosterone-induced benign prostatic hyperplasia in rats by reducing oxidative stress and inflammation, indicating its potential as a therapeutic option for managing BPH through specific signaling pathways.