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Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Tempol is safe and may prevent hair loss from brain radiotherapy.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Eating disorders like anorexia and bulimia cause skin problems, and dermatologists can help detect these disorders early for better treatment outcomes.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Fat cells in the skin help start healing and form important repair cells after injury.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.