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Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.

Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

DHT stops hair regrowth in mice, similar to human hair loss.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

The study aims to find the best treatment for central serous chorioretinopathy by comparing various options.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

Hair growth and health are influenced by stress and hormones.

Most patients experienced hirsutism again after stopping hormone treatment, indicating long-term treatment is needed to maintain results.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Platelet-rich plasma (PRP) treatment has been found effective in promoting hair growth for alopecia patients, with minimal side effects like temporary pain and redness.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.

Intense exercise at night can delay the body's internal clock gene expression by 2 to 4 hours.

Looking at skin can help find and treat serious diseases early.

The exact cause of growth hormone-responsive alopecia in dogs is unclear.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

The research suggests that autophagy-related genes might play a role in causing alopecia areata.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.