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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

Hair loss affects self-esteem and quality of life; treatments can help.

Current treatments for alopecia show no significant long-term benefits.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Bimatoprost is a safe and effective treatment for making eyelashes longer, thicker, and darker.

Some systemic treatments work for nail psoriasis but can have serious side effects.

The study found that family history, personal history of adolescent acne, no pregnancies, hirsutism, office work, stress, and low intake of fruits/vegetables and fish are risk factors for adult female acne.

Non-ablative and ablative fractional lasers helped hair growth in some cases without major side effects, but didn't work for all hair disorders.

PRP shows promise for hair loss treatment, with three initial monthly injections and maintenance every 3-6 months.

Bimatoprost solution is effective and safe for long-term use in treating eyelash thinning.

PRP treatment improves hair density and thickness for alopecia, but needs more research.

Fractional resurfacing is safe and effective for certain skin conditions in Asian patients, but care must be taken to avoid skin pigmentation issues.

PRP treatment helps hair growth and density with 70.7% success, but more research needed.

Dental erosion is common in adolescents and is linked to diet and higher socioeconomic status.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.

Platelet-rich plasma therapy helps improve atrophic acne scars.

Latanoprost works better for hair growth, and combining it with betamethasone valerate is most effective.

Direct brow lifting is effective, safe, and provides excellent long-lasting results for bald men or those with a high hairline.

Topical calcineurin inhibitors, especially 0.1% tacrolimus ointment, are effective and well-tolerated for treating cutaneous lupus erythematosus but require more research for standard treatment guidelines.

Electrospun scaffolds can improve healing in diabetic wounds.

Some off-label treatments increase hair density, but long-term safety unknown.

New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.

Finasteride and intense pulsed light effectively reduce unwanted facial hair in women, but may not be cost-effective.

Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.

PRGF treatments increased hair number and thickness in people with hair loss, with more injections leading to better results.

Animal models, especially mice, are essential for advancing hair loss research and treatment.

The document concludes that better tools are needed to measure skin disease severity in dermatomyositis and cutaneous lupus erythematosus, and introduces the DSSI and CLASI as reliable instruments.