September 2012 in “The Egyptian Journal of Histology” In this study, flutamide at therapeutic doses caused significant histological changes in the testes and epididymis of adult albino rats, reducing androgen receptor immunoreactivity and increasing estrogen receptor immunoreactivity.
September 2002 in “Comprehensive Therapy” Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.
March 2026 in “International Journal of Homoeopathic Sciences” This review discusses the growing problem of alopecia and suggests that homeopathy, alongside lifestyle changes, may effectively manage different types of hair loss, though it reports no new clinical findings.
60 citations
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February 2010 in “Gynecological Endocrinology” This study suggests that adding metformin to diet and exercise improves insulin resistance and hyperandrogenism in women with PCOS, though lifestyle changes alone may enhance menstrual cycles.
43 citations
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October 2019 in “Pediatric Research” This review discusses the International Evidence-Based PCOS Guidelines, which aim to improve diagnosis and management of PCOS and its associated comorbidities, noting the importance of early intervention and healthy lifestyle changes; it reports no new results.
29 citations
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January 2011 in “Journal of Obstetrics and Gynaecology” This review discusses insulin resistance in women with polycystic ovary syndrome and reports no new clinical results; it highlights the potential benefits of lifestyle changes and insulin-sensitizing drugs.
8 citations
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August 2011 in “Journal of Medicinal Food” In this study, D-004 did not affect androgen-dependent development in rats exposed in utero, while finasteride caused significant changes in male offspring's androgen-dependent tissues.
3 citations
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August 2017 in “Journal of evolution of medical and dental sciences” In this descriptive study, elderly patients most commonly presented with skin wrinkling, xerosis, and eczematous conditions, highlighting the difficulty in distinguishing normal age-related from pathological skin changes.
1 citations
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October 2022 in “Curēus” This case report highlights the challenges in diagnosing simple-virilizing congenital adrenal hyperplasia, emphasizing the importance of early expert evaluation to prevent irreversible changes such as virilization.
April 2026 in “Research Square” This study found that COVID-19 infection disrupts spermatogenesis, alters testicular cell populations, and may impact male fertility by causing long-term changes in testicular function and reduced sperm quality, as observed even in patients who have recovered from the acute phase of the infection.
May 2025 in “International Journal of Clinical Obstetrics and Gynaecology” This article reviewed literature from 2013-2023 and found that while varied treatment options for PCOS exist, managing the condition holistically, including lifestyle changes and gastric bypass surgery, can significantly improve symptoms and quality of life without worsening side effects.
November 2016 in “Journal of Evolution of Medical and Dental Sciences” This study observed that among elderly patients, the most common systemic disease associated with skin conditions was diabetes, while wrinkling and xerosis were prevalent skin changes.
In this study, researchers found that alopecia areata is linked to immune cell activation against hair follicle autoantigens and is associated with heart changes and cardiac marker alterations in humans and mice.
July 2003 in “Journal of Cutaneous Medicine and Surgery” Blood pressure drugs can cause skin lupus, early treatment is key for baby herpes and diabetic foot ulcers, a certain vaccine works against genital herpes and HPV in women, more frequent light therapy helps psoriasis, smoking and drinking can worsen psoriasis, a cream clears up a type of skin cancer, and low iron levels don't cause chronic hair loss.
July 2003 in “Journal of Cutaneous Medicine and Surgery” High blood pressure drugs often cause skin lupus, stopping the drug usually helps. A vaccine helps prevent genital herpes and HPV-16. More frequent light therapy clears psoriasis faster. No link was found between low iron and chronic hair loss.
July 2003 in “Journal of Cutaneous Medicine and Surgery” Blood pressure drugs can cause skin lupus, but it improves after stopping the drug. The glycoprotein D vaccine works against genital herpes in some women, and the HPV-16 vaccine reduces HPV-16 infection and related diseases. More frequent light therapy clears psoriasis faster. A cream called imiquimod effectively treats a type of skin cancer. Iron supplements don't necessarily help with chronic hair loss in women.
September 1985 in “Journal of The American Academy of Dermatology” Dr. Rasmussen disagrees with Alexander and Schor, emphasizing uncertainty in genital wart transmission and advocating for discussions on potential abuse and referrals in such cases.
4 citations
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September 2016 in “Journal der Deutschen Dermatologischen Gesellschaft” This study found that 7.9% of dermatological outpatients at a German hospital had clinically relevant body dysmorphic concerns, highlighting the need for psychotherapeutic support due to poor social adaptation and high motivation for change.
1 citations
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January 2013 in “Elsevier eBooks” The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.
This study reports that prostatitis, affecting many men aged 30 to 50, arises from diverse causes, including bacterial infections and pelvic pain syndromes, and requires treatment strategies specific to its type, such as antibiotics and lifestyle changes.
January 2024 in “Archives of pharmacy practice” This study reviews the embryological origins, anatomical and histological structure, and key functions of the skin, emphasizing its protective, sensory, and regulatory roles, as well as the social and psychological impacts of post-lesion changes.
July 2003 in “Journal of Cutaneous Medicine and Surgery” Certain drugs can cause lupus, stopping these drugs is the main treatment. NB-UVB phototherapy clears psoriasis faster when applied three times a week. Monoclonal antibodies and oral pimecrolimus are effective in treating psoriasis. Smoking and drinking are linked to psoriasis in men. No direct link between low iron and hair loss was found. Vaccines are effective against genital herpes and human papillomavirus type 16.
January 1983 in “Elsevier eBooks” Masculinization in affected individuals occurs gradually after puberty due to hormone changes.
102 citations
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July 2020 in “International journal of molecular sciences” This review discusses the effects of hormonal changes on hair follicles, concluding that hormones like androgens and estradiol significantly influence hair growth and cycle, while the roles of other hormones are still being researched.
2 citations
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July 2024 in “International Journal of Transgender Health” This study reviewed literature on dermatological changes in transgender and gender diverse individuals during gender affirming medical transition, identifying risks like acne and hypertrophic scars, and provided tailored care recommendations for health professionals.
10 citations
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August 2012 in “Current Problems in Pediatric and Adolescent Health Care” This review explores hair signs related to nutrition disorders, such as thin and dyspigmented hair, without presenting new clinical findings; the authors highlight unknowns regarding underlying causes.
June 1993 in “Current opinion in therapeutic patents” This study reports that novel hexahydrobenzoquinolin compounds fully inhibited 5α-reductase activity in human genital skin fibroblasts, suggesting their potential for treating conditions like benign prostatic hyperplasia and male pattern baldness.
15 citations
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January 2020 in “ILAR Journal” This review discusses the occurrence and impact of background histopathologic changes in nonhuman primate research, emphasizing the importance of understanding these factors to enhance study validity and interpretation.
December 2024 in “Nutrients” In this review, skin changes like hair loss and brittle nails linked to nutritional deficiencies common in eating disorders are examined as critical diagnostic tools, highlighting the need for integrated care involving dermatologists, psychiatrists, and nutritionists for effective management.
4 citations
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June 2017 in “Endocrine Reviews” Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.