15 citations
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July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses the potential of induced pluripotent stem cells (iPSCs) for generating skin components, particularly for genetic skin disorder modeling and gene-corrected regenerative therapies, but reports no new clinical results.
3 citations
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August 2021 in “Veterinary dermatology” This review discusses the biology and pathology of hair growth, exploring novel therapies like sublingual minoxidil and Janus kinase inhibitors, but reports no new clinical data.
336 citations
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August 2015 in “European Journal of Epidemiology” This article reviews the design and objectives of the Rotterdam Study, as well as summarizes major findings, without reporting new results.
150 citations
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October 2010 in “The American Journal of Pathology” This review discusses the pathogenesis and challenges in treating primary cicatricial alopecia, highlighting the need to understand immune protection collapse in hair follicle stem cells; it reports no new clinical results.
65 citations
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November 2012 in “Tissue Engineering Part B-reviews” This review discusses the biology of hair follicle stem cells and highlights their potential for applications in regenerative medicine, drug, and gene delivery, but reports no new clinical results.
January 2026 in “Frontiers in Oncology” This case report highlights that in postmenopausal women with severe hyperandrogenism, thorough adrenal and pelvic evaluations, hormonal profiling, and permanent pathology are essential for accurate diagnosis and management of androgen-secreting tumors, such as AGCTs, to prevent misdiagnosis and ensure effective treatment.
269 citations
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October 2017 in “International Journal of Molecular Sciences” This review examines the challenges of cell engraftment in regenerative medicine and discusses potential strategies to improve the efficacy of cell-based therapies, including cell-free regenerative approaches.
99 citations
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July 2017 in “Clinical Reviews in Allergy & Immunology” This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.
62 citations
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January 2010 in “Hormone research in paediatrics” This study found that the R257X mutation in the AIRE gene is prevalent among Russian patients with autoimmune polyglandular syndrome type 1, particularly in those with hypoparathyroidism and chronic mucocutaneous candidiasis.
34 citations
,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses advancements in gene delivery to hair follicles and suggests potential gene therapy applications for treating hair loss, but it reports no new experimental results.
15 citations
,
January 1987 in “Electrophoresis” This study found that electrophoretic keratin typing of head hair can identify specific polypeptide patterns, suggesting potential applications in genetic and forensic investigations.
14 citations
,
January 2015 in “Current problems in dermatology” This review addresses treatment approaches for female pattern hair loss, highlighting that combining different therapies may be more effective than single treatments, but no new results are reported.
8 citations
,
February 2025 in “Cell Systems” This study developed a genetic toolbox to engineer Cutibacterium acnes for dermal applications, successfully creating a strain that secretes antioxidants to reduce oxidative stress in a UV stress model.
7 citations
,
November 2018 in “British Journal of Dermatology” Alopecia areata is caused by immune system issues, and JAK inhibitors might help treat it.
1 citations
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September 2024 in “Benha Journal of Applied Sciences” This review provides an overview of androgenetic alopecia, detailing its causes, diagnostic methods, and current treatments, noting that combination therapies show promise but newer options like cell-based treatments require more research.
June 2026 in “International Journal of Drug Delivery Technology” This study highlights the potential of polymeric micelles in enhancing the targeted delivery and efficacy of treatments for androgenetic alopecia, by offering improved retention on the scalp, extended release, and reduced systemic side effects compared to conventional therapies like minoxidil and finasteride.
March 2026 in “International Journal of Innovative Technologies in Social Science” This review highlights advancements in vitiligo treatment, noting improved diagnostic techniques and the emergence of targeted therapies like Janus Kinase inhibitors, which may offer more effective management of this complex autoimmune skin disorder.
March 2026 in “Aging Research” This review provides a comprehensive synthesis of skin aging research, highlighting the interplay of genetic and environmental factors, cellular mechanisms, and advances in diagnostic and therapeutic strategies, while also addressing current debates and future directions in the anti-aging field.
December 2024 in “Benha Journal of Applied Sciences” This study reports that combination therapies, including surgical and various medical treatments, show promise for managing androgenetic alopecia, though further research is necessary to confirm the safety and effectiveness of emerging therapies.
May 2024 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)” This study investigated genetic and epigenetic markers for prostate cancer, reporting that certain genotype combinations may influence cancer risk or protection and identifying GSTP1 promoter methylation as a strong prognostic and diagnostic marker linked to tumor aggressiveness.
January 2024 in “Academic Journal of Medicine & Health Sciences” This study highlights a novel herbal tea blend that may improve hair health and provide anti-aging benefits, though its efficacy requires further scientific validation.
This study found that human hair follicles can be used to generate induced pluripotent stem cells, which can then efficiently differentiate back into keratinocytes.
January 2013 in “Российский журнал кожных и венерических болезней” This article reviews the pathophysiology and limited effectiveness of current treatments for androgenic alopecia, including finasteride, minoxidil, botulinum toxin A, and platelet-rich plasma, and highlights the need for new therapeutic approaches; it reports no new clinical findings.
February 2023 in “Journal of Aesthetic Nursing” This source reviewed various methods for hair restoration in men and women, emphasizing clinical approaches and treatment options but did not report specific outcomes.
January 2023 in “Journal of Dermatological Treatment” This case report describes a 14-year-old patient with hereditary hypotrichosis simplex who showed significant improvement with combined platelet rich plasma injections and topical minoxidil 2%. The findings suggest that platelet rich plasma could offer new hope for treating this condition.
39 citations
,
January 2018 in “British journal of dermatology/British journal of dermatology, Supplement” This review highlights that although acne and hidradenitis suppurativa share a focus on hair follicles and innate inflammation, their genetics, risk factors, and bacterial involvement differ significantly.
11 citations
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February 2019 in “Research and reports in forensic medical science” This article discusses the use of forensic DNA phenotyping to infer physical characteristics from biological samples without a reference sample, aiding investigations but raising ethical and legal concerns.
This study identified CD28 as a promising drug target for treating alopecia areata, using a multi-omics approach to highlight its role in immune regulation and linking it to favorable safety profiles, thus offering a strategy for autoimmune target discovery.
This study identified CD28 as a potential drug target in treating alopecia areata by linking immune signaling pathways to local inflammation, highlighting belatacept as a promising treatment option due to minimal adverse effects and providing insights into autoimmune target discovery.
480 citations
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August 2014 in “Nature Biotechnology” This review discusses manipulating the stem cell niche as a strategy in regenerative medicine to repair damaged tissues, highlighting the potential benefits and challenges but reporting no new results.