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PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Adrenal disorders can cause lasting brain and behavior issues in children.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Hair problems are common and distressing for women, but increasing knowledge of treatments offers hope.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Minoxidil effectively treats female pattern hair loss.

Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Alopecia Areata is a complex, unpredictable autoimmune hair loss condition with limited treatment options and a significant psychological impact.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.

Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

Hypaphorine from a fungus changes the internal structure of Eucalyptus root hairs, stopping their growth.

Finasteride effectively treats male hair loss, improving growth and density.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.