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Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

PLD is an effective and safer alternative for treating breast cancer.

PRP injections improve hair thickness for baldness.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

Growth factors are crucial for hair development and could help treat hair diseases.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Children with loose anagen hair have easily pluckable hair due to root sheath problems, and it might improve without treatment.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Latanoprost 0.1% may effectively treat hair loss.

Follistatin helps hair growth and cycling, while activin prevents it.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

New treatments for male hypogonadism are effective and should be personalized.

Targeting the skin's endocannabinoid system could help treat skin disorders.