This study found flutamide to be an effective long-term treatment for female pattern hair loss with improved alopecia scores and high compliance when using very low doses, though some potential for hepatic disorders was observed initially.
January 2025 in “Mansoura Medical Journal” This research observed that some hypothyroid patients on adequate levothyroxine therapy continue to experience symptoms like poor concentration and hair loss, with findings suggesting an elevated anti-TPO level increases the likelihood of such symptoms, despite normal TSH levels.
January 2021 in “Hair transplant forum international” This article describes a new T-Fast multi-implanter that potentially reduces operating costs and surgical time by implanting two follicular unit excision grafts simultaneously, which may encourage clinics to adopt this technique.
July 2022 in “Journal of Cosmetic Dermatology” This study found that in patients with frontal fibrosing alopecia, combining topical tacrolimus with isotretinoin is more effective after four weeks of treatment compared to tacrolimus with finasteride, though both regimens offered some benefit.
22 citations
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May 1986 in “Clinics in endocrinology and metabolism” This study found that women with lower 2D:4D ratios and fewer middle-phalangeal hairs reported more adverse side effects from oral contraceptives, suggesting these features may predict hormonal contraceptive side effects.
13 citations
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August 2002 in “Dermatologic Surgery” This paper introduces Follicular Unit Extraction and reports the FOX Test can identify suitable candidates, with about 25% of patients being ideal and 35% being good candidates for the procedure.
95 citations
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August 2013 in “Journal of Investigative Dermatology” HPT axis hormones boost mitochondrial function and growth in hair follicles, potentially aiding hair health.
November 2020 in “Dubai medical journal” This case report described a 24-year-old with alopecia totalis who saw full scalp hair regrowth by the 9th month while using oral tofacitinib, which was well-tolerated and did not show serious adverse effects. Longer-term studies are needed to confirm its overall effectiveness for alopecia totalis.
17 citations
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May 2011 in “Movement Disorders” Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.
August 2018 in “Journal of Investigative Dermatology” This study of alopecia areata patients found that a 10 mg twice-daily dose of oral tofacitinib led to significant hair regrowth, suggesting it may be beneficial for treatment.
23 citations
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January 2012 in “International Food Research Journal” This case report describes a 39-year-old woman whose dermatomyositis-systemic lupus erythematosus overlap syndrome symptoms resolved after switching to tofacitinib.
70 citations
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April 2016 in “Experimental Dermatology” In this study, oral tofacitinib treatment led to significant hair regrowth and changes in skin and blood biomarkers in a patient with alopecia areata.
22 citations
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November 1979 in “Archives of dermatology” This report describes a case where topical 0.1% tretinoin cream successfully controlled Fox-Fordyce disease in a 21-year-old woman.
November 2025 in “Journal of Investigative Dermatology” Certain immune cells in atopic dermatitis skin could be targeted for treatment.
December 2009 in “생명과학회지” This study found that thymosin β4 is highly expressed in multiple human tissues and may play a role in organ function and angiogenesis through co-localization with VEGF.
September 2022 in “Journal of the American Academy of Dermatology” This study observed that tofacitinib therapy over about 16 weeks had a positive effect in children with alopecia areata, reducing the SALT index significantly in some patients.
5 citations
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January 2018 This study optimized a screening assay to identify molecules that inhibit or enhance TRPM5 ion channel activity, which may have implications for treating dysfunctions linked to cardiac arrhythmias and diabetes.
December 2013 in “대한피부과학회지” In this study, Korean women with female pattern hair loss were found to have higher levels of ferritin, testosterone, and vitamin D compared to the average Korean adult women.
In this study, researchers developed a chemiluminescence assay kit for detecting free testosterone, showing it performed well and met clinical demands with low cost and automation; free testosterone levels differed in patients with various diagnoses, suggesting its diagnostic relevance for diseases such as prostate malignancy.
August 2023 in “Journal of Cosmetic Dermatology” This study observed that in a mouse model of androgenetic alopecia, treatments with LTF, 5% minoxidil, and LTF-DPC-EXO significantly promoted hair regeneration compared to the model group, potentially through modulation of the PI3K/AKT signaling pathway.
4 citations
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January 2005 This study found a significant association between low serum ferritin levels and chronic telogen effluvium in menstruating women, with iron treatment improving hair growth in those affected.
January 2018 in “International journal of medical biochemistry” This study found that female patients with telogen effluvium had significantly lower levels of serum ferritin, folate, and vitamin B12 compared to the control group.
990 citations
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October 1999 in “Development” This study found that LEF1/TCF3 is necessary but not sufficient for TOPGAL activation in hair follicle development, indicating complex regulation in the skin.
188 citations
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October 2014 in “Thyroid” This study found that dabrafenib was well tolerated and led to durable responses in patients with BRAF-mutant differentiated thyroid carcinoma, with a median progression-free survival of 11.3 months.
November 2023 in “Indian Dermatology Online Journal” This study found that tofacitinib was safe and effective for patients with severe or treatment-resistant alopecia areata, alopecia totalis, and alopecia universalis, resulting in significant hair regrowth for most participants.
1 citations
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October 2020 in “PubMed” In this study, nearly half of the female patients with androgenetic alopecia reported symptoms of hormonal disorders, but hormone test results did not show significant abnormalities.
105 citations
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February 2010 in “Endocrinology” This study found that normal human epidermis expresses TSH and may be an indirect target of TSH signaling, with expression regulated by endocrine controls of the hypothalamic-pituitary-thyroid axis.
April 2018 in “Journal of Investigative Dermatology” In this study, topical tofacitinib significantly promoted hair regrowth in mice, outpacing both minoxidil and controls over 21 days, with findings suggesting increased VEGF levels and decreased inflammation as possible mechanisms.
February 2026 in “European Urology” January 2026 in “Endocrinology”