March 2025 in “Journal of Clinical Medicine” This review discusses the unique clinical features, challenges in diagnosis, and treatment protocols of frontal fibrosing alopecia in men, noting the overlap with other types of alopecia and the need for further studies.
1 citations
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April 2018 in “Journal of Investigative Dermatology” This study found that FZD2 is crucial for hair follicle formation and postnatal growth in mice and has a novel role in regulating early epidermal development, including stratification and cornification.
10 citations
,
January 2010 in “Veterinary pathology” This study found that a newly identified mutation in the hairless gene in mice led to decreased Hr mRNA levels and changes in gene expression related to hair follicle development.
11 citations
,
January 2007 in “Veterinary dermatology” This study found that administerating 10 mg/kg intramuscular fulvestrant did not stimulate hair regrowth in Pomeranian dogs with alopecia X, though higher doses may warrant further investigation.
8 citations
,
March 2012 in “Mass spectrometry letters” This study observed that the isotope-dilution GC-MS technique can assess 5α-reductase activity more effectively than conventional methods in rat liver S9 fractions, particularly at low testosterone levels.
This review concluded that 5α-reductase inhibitors like finasteride and dutasteride offer limited additional feminising effects in hormone therapy for transfeminine individuals, with the clearest use being androgenetic alopecia treatment; more research is needed for other potential benefits.
29 citations
,
February 2010 in “British Journal of Dermatology” This study explores the expression of Snail1 in the fibrotic dermis of postmenopausal women with frontal fibrosing alopecia, suggesting a possible link to epithelial-mesenchymal transition.
January 2025 in “International Journal of Scientific Research” This study found that female pattern hair loss was present in 12.5% of PCOS patients examined, with most cases in younger women, highlighting early detection and management importance.
61 citations
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January 2019 in “American Journal of Clinical Dermatology” This review discusses the potential causes and treatments for frontal fibrosing alopecia but reports no new clinical findings, highlighting the need for further research to understand its pathogenesis and develop validated treatments.
January 2024 in “Hair transplant forum international” This source provides information about the 32nd Annual ISHRS Congress, which is focused on hair restoration surgery education, research, and collegiality, with a strong emphasis on education. However, results or further details of the congress are not reported.
September 2018 in “Dermatologic Therapy” This article is a commentary on another piece about the clinical efficacy of oral finasteride and reports no new results.
26 citations
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September 2005 in “Pharmacology Biochemistry and Behavior” This study found that inhibiting the 5alpha-reductase 2 pathway in male rats affects brain sexual differentiation and leads to reproductive changes, including increased pre-implantation loss despite unchanged copulatory potential.
2 citations
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January 2010 in “PubMed” This case report observed no hair regrowth after treating a woman with postmenopausal frontal fibrosing alopecia using systemic and local corticosteroids, suggesting the need for more innovative therapies.
February 2021 in “Pakistan Armed Forces Medical Journal” This article presents a case study of favoure racouchot syndrome involving the scalp in a farmer, which has not been previously described as part of this condition, but offers no new research findings.
June 1996 in “Journal of Dermatological Science”
10 citations
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January 2003 in “Seminars in reproductive medicine” This review covers the pathophysiology, diagnosis, evaluation, and treatment of hirsutism and reports no new clinical findings.
January 2025 in “Revista del Centro Dermatológico Pascua” Early diagnosis and treatment can help manage fibrosing alopecia in older women.
2 citations
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January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that low temperatures and nitrogen deficiency trigger root hair elongation through a molecular mechanism involving the receptor kinase FERONIA and the TOR Complex 1.
9 citations
,
June 2020 in “BMC Molecular and Cell Biology” This study found that stress hormones, particularly CRF, can inhibit hair growth and induce hair loss by affecting human dermal papilla cells and hair follicles, suggesting a functional HPA axis in these cells.
16 citations
,
January 2007 in “Archives of Iranian Medicine” In this study of premenopausal Iranian women with hirsutism, polycystic ovary syndrome was a common cause and frequently associated with menstrual irregularity, while elevated androgens or hyperandrogenic conditions were also observed.
6 citations
,
November 2007 in “British Journal of Dermatology” This study found that topical fulvestrant did not significantly improve hair growth parameters in men and postmenopausal women with androgenetic alopecia, unlike minoxidil, which was more effective in men.
January 2025 in “SSRN Electronic Journal”
451 citations
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March 2005 in “Endocrine Reviews” This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.
1 citations
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January 2020 in “Skin appendage disorders” Finasteride may help treat frontal fibrosing alopecia, but more research is needed.
July 2025 in “International Society of Hair Restoration Surgery” This article discusses initiatives by the ABHRS to enhance hair restoration surgery standards but presents no new research findings.
January 2023 in “International Journal of Pharmaceutical and Clinical Research” This review highlights the potential of follicular targeting as a novel approach for treating hirsutism, focusing on its ability to improve outcomes and reduce side effects, but reports no new clinical results.
63 citations
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November 1999 in “British journal of dermatology/British journal of dermatology, Supplement” This study observes the expression of mRNA for androgen receptor, 5α‐reductase, and 17β‐hydroxysteroid dehydrogenase in human dermal papilla cells.
September 2025 in “Journal of the American Academy of Dermatology” Using 5α-reductase inhibitors for hair loss in women doesn't increase cancer risk.
1 citations
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April 2021 in “Journal of The American Academy of Dermatology” Some overweight or obese men with long-term frontal fibrosing alopecia may have abnormal sex hormone levels.
4 citations
,
January 1996 in “PubMed” This study found that after 12 months of treatment with 5 mg of finasteride, patients with benign prostatic hyperplasia showed reduced prostate volume, DHT and PSA levels, and improved urinary flow rates and symptoms.